Comprehensive Information

Detailed Information (Experimental Results)

Top

Database ID12
UniProt ID A1JUA6 
Name Uncharacterized protein
Type Type III secretion system effector (T3SE)
Gene Name YEP0050
Organism Yersinia enterocolitica serotype O:8 / biotype 1B
Gene Ontology Terms GO:0004725;GO:0009405
Function -
Sequence MNLSLSDLHRQVSRLVQQESGDCTGKLRGNVAANKETTFQGLTIASGARESEKVFAQTVLSHVANIVLTQEDTAKLLQSTVKHNLNNYELRSVGNGNSVLVSLRSDQMTLQDAKVLLEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLAPRTPPLPPRERPHTSGHHGAGEVRATAPSTVSPYGPEARAELSSRLTTLRNTLTPATNDPRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNTRTIACQYPLQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYGSITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALASLVDQTAETKRNMYESKGSSAVADDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQGRPLLNS
Length 468  amino acids
Reference 24391954
IBS
There is no IBS picture for this protein entry.
Sequence Alignment:

Protein Structure (Experimental Results)

Top

PDB Accession Method Resolution Chain Structure Review
Sorry. There is no result for this protein entry.

Disorder Prediction (Computational Results)

Top

Start End Sequence
364 364 V
117 217 LEAALRQESGARGHVSSHSHSVLHAPGTPVREGLRSHLAPRTPPLPPRERPHTSGHHGAGEVRATAPSTVSPYGPEARAELSSRLTTLRNTLTPATNDPRY
375 395 TAETKRNMYESKGSSAVADDS
104 113 RSDQMTLQDA
461 468 QGRPLLNS
1 26 MNLSLSDLHRQVSRLVQQESGDCTGK
419 452 MNDSRNSQLSVEDMVSQMRVQRNGIMVQKDEQLD
51 51 S
97 97 N

Disorder Picture (Computational Results)

Top

Kinase-specific Phosphorylation Sites (Computational Results)

Top

Position Code Kinase Peptide Score Cutoff
395 S Other/PLK SSAVADDSKLRPVIH 13.539 8.093
38 T AGC/PDK1/PKH1 VAANKETTFQGLTIA 12.333 4.167
158 T Atypical/PIKK/FRAP RSHLAPRTPPLPPRE 25.889 8.145
4 S CK1/VRK/VRK2 ****MNLSLSDLHRQ 26.75 4
279 T CMGC/MAPK/ERK/Erk1 RMLAENRTPVLAVLA 15.639 10.326
38 T STE/STE20/YSK VAANKETTFQGLTIA 11 6.05
37 T STE/STE20/PAKA/PAK3 NVAANKETTFQGLTI 18.333 5.9
468 S AGC/PKC/PKCa/PRKCA QGRPLLNS******* 25.136 5.842
203 T CMGC/DYRK/DYRK2 ELSSRLTTLRNTLTP 12.611 7.053
6 S CMGC/CDK/CDK2/CDK2 **MNLSLSDLHRQVS 14.04 6.826
51 S Other/AUR/AurB IASGARESEKVFAQT 11.556 7.092
158 T CMGC/MAPK RSHLAPRTPPLPPRE 12.225 4.55
181 T Other/CDC7 GAGEVRATAPSTVSP 12.333 9.583
385 S Other/CDC7/CDC7 TKRNMYESKGSSAVA 11 9.583
202 T STE/STE20/PAKA AELSSRLTTLRNTLT 11.244 6.397
279 T CMGC/MAPK/JNK/JNK2 RMLAENRTPVLAVLA 26.5 6.118
209 T CMGC/MAPK/ERK/Erk2 TTLRNTLTPATNDPR 13.482 4.61
468 S AGC/GRK/BARK/BARK1 QGRPLLNS******* 22.31 3.384
13 S CK1/VRK/VRK2 SDLHRQVSRLVQQES 12 4
4 S CK1 ****MNLSLSDLHRQ 24.576 5.313
318 T AGC/DMPK/ROCK ITVESKMTQQVGLGD 13.29 6.326
46 S TKL/LISK/LIMK FQGLTIASGARESEK 14 6
144 T CMGC/MAPK SVLHAPGTPVREGLR 12.347 4.55
13 S AGC/RSK/RSKp70/RPS6KB2 SDLHRQVSRLVQQES 11.333 5.033
187 S CMGC/CDK/CDK2/CDC28 ATAPSTVSPYGPEAR 14.806 9.411
207 T STE/STE20/YSK RLTTLRNTLTPATND 11 6.05
13 S CAMK/MAPKAPK/MK5/MAPKAPK5 SDLHRQVSRLVQQES 14.182 6.633
125 S STE/STE20/PAKA/PAK1 EAALRQESGARGHVS 11.421 6.979
125 S AGC/RSK/MSK/RPS6KA5 EAALRQESGARGHVS 12.074 8.69
135 S Other/PLK/PLK2 RGHVSSHSHSVLHAP 11.023 5.114
144 T CMGC/CDK/CDK5 SVLHAPGTPVREGLR 15.192 6.616
209 T CMGC/CDK/CDK5 TTLRNTLTPATNDPR 14.404 6.616
202 T Other/TTK/TTK AELSSRLTTLRNTLT 52.636 47.968
248 Y TK/Met/RON RADLNANYIQVGNTR 14.5 9.3
133 S CAMK/PIM GARGHVSSHSHSVLH 14.238 4.683
187 S CMGC/CDK/CDK5 ATAPSTVSPYGPEAR 18.071 6.616
217 Y TK/PDGFR/PDGFRA PATNDPRYLQACGGE 15.1 8.814
38 T STE/STE20/MST/MST1 VAANKETTFQGLTIA 46.226 2.612
361 S CAMK/MAPKAPK/MK5/MAPKAPK5 WPDQTAVSSEVTKAL 12 6.633
287 S Other/CDC7/CDC7 PVLAVLASSSEIANQ 11.667 9.583
209 T CMGC/MAPK/ERK/Erk1 TTLRNTLTPATNDPR 20.688 10.326
144 T CMGC/MAPK/ERK/Erk2 SVLHAPGTPVREGLR 19.642 4.61
203 T CAMK/CAMKL/CHK1 ELSSRLTTLRNTLTP 11.931 8.03
209 T CMGC/CDK/CCRK/CDK20 TTLRNTLTPATNDPR 11.25 5.888
144 T CMGC/MAPK/p38 SVLHAPGTPVREGLR 12.948 4.309
189 Y TK/Jak/JAK2 APSTVSPYGPEARAE 12.341 9.766
80 T STE/STE20/MSN/TNIK TAKLLQSTVKHNLNN 12 7
125 S AGC/RSK/RSKp90/RPS6KA3 EAALRQESGARGHVS 11 8.112
125 S AGC/PKG/PRKG1 EAALRQESGARGHVS 12.633 6.847
158 T CMGC/CDK/CDK2/CDK2 RSHLAPRTPPLPPRE 12.02 6.826
46 S TKL/LISK FQGLTIASGARESEK 12.25 3.062
315 S Other/CDC7 YGSITVESKMTQQVG 11 9.583
315 S Other/CDC7/CDC7 YGSITVESKMTQQVG 11 9.583
187 S CMGC/MAPK/p38/HOG1 ATAPSTVSPYGPEAR 13.2 7.46
187 S CMGC/MAPK/ERK/Erk1 ATAPSTVSPYGPEAR 15.479 10.326
365 T CAMK/MAPKAPK/MK5 TAVSSEVTKALASLV 13.182 6.633
279 T CMGC/CDK/CDK2/CDK2 RMLAENRTPVLAVLA 12.564 6.826
69 T STE/STE7/MEK1/MAP2K2 HVANIVLTQEDTAKL 11 7
185 T STE/STE20/MSN/MAP4K4 VRATAPSTVSPYGPE 12 7
13 S AGC/PKC/PKCi SDLHRQVSRLVQQES 12.188 7.442
301 Y TK/Trk/TRKA QRFGMPDYFRQSGTY 24.2 11.95
203 T CAMK/CAMKL/PASK/PASK ELSSRLTTLRNTLTP 14 5.4
133 S CAMK/PIM/PIM1 GARGHVSSHSHSVLH 18.385 5.965
312 T STE/STE20/MST/MST1 SGTYGSITVESKMTQ 17.516 2.612
187 S Atypical/PIKK/FRAP ATAPSTVSPYGPEAR 12.222 8.145
468 S AGC/GRK/BARK QGRPLLNS******* 13.744 3.806
13 S CAMK/MAPKAPK/MK5 SDLHRQVSRLVQQES 14.182 6.633
385 S Other/CDC7 TKRNMYESKGSSAVA 11 9.583
375 T Other/PLK/PLK1/CDC5 LASLVDQTAETKRNM 11.222 5.642
51 S Other/CDC7/CDC7 IASGARESEKVFAQT 12.667 9.583
383 Y TK/Abl/ABL1 AETKRNMYESKGSSA 12.259 5.557
158 T CMGC/MAPK/JNK/JNK2 RSHLAPRTPPLPPRE 34.824 6.118
13 S AGC/PKG/PRKG1 SDLHRQVSRLVQQES 11.933 6.847
468 S Atypical/PDHK/PDHK QGRPLLNS******* 14.375 2.805
332 Y TK/Trk/TRKA DGIMADMYTLTIREA 20.8 11.95
80 T STE/STE20/MSN/MINK1 TAKLLQSTVKHNLNN 12 7
187 S CMGC/CDK/CDK5/CDK5 ATAPSTVSPYGPEAR 18.975 7.867
37 T Other/NEK/NEK11 NVAANKETTFQGLTI 11 8.933
187 S CMGC/MAPK/ERK/Erk2 ATAPSTVSPYGPEAR 11.748 4.61
361 S CAMK/MAPKAPK/MK5 WPDQTAVSSEVTKAL 12 6.633
13 S CAMK/CAMKL/CHK1 SDLHRQVSRLVQQES 11.379 8.03
158 T CMGC/MAPK/p38 RSHLAPRTPPLPPRE 13.615 4.309
181 T Other/CDC7/CDC7 GAGEVRATAPSTVSP 12.333 9.583
365 T CAMK/MAPKAPK/MK5/MAPKAPK5 TAVSSEVTKALASLV 13.182 6.633
187 S CMGC/CDK/CDC2/CDK1 ATAPSTVSPYGPEAR 11.738 4.168
46 S TKL/LISK/LIMK/LIMK1 FQGLTIASGARESEK 14 6
144 T CMGC/CDK/CDK2/CDC28 SVLHAPGTPVREGLR 13.75 9.411
345 S STE/STE20/PAKA/PAK1 EAGQKTISVPVVHVG 12.053 6.979
80 T STE/STE20/MST TAKLLQSTVKHNLNN 11.026 3.532
6 S CK1 **MNLSLSDLHRQVS 14.104 5.313
468 S Other/PEK QGRPLLNS******* 32.045 2.678
158 T CMGC/CDK/CDK5/CDK5 RSHLAPRTPPLPPRE 11.099 7.867
169 T CMGC/DYRK/DYRK2 PPRERPHTSGHHGAG 15 7.053
185 T Other/TTK/TTK VRATAPSTVSPYGPE 49.455 47.968
428 S CK1/CK1/CK1-D/CSNK1D DSRNSQLSVEDMVSQ 14.25 8.142
169 T Other/TTK/TTK PPRERPHTSGHHGAG 57.364 47.968
144 T CMGC/MAPK/ERK/Erk1 SVLHAPGTPVREGLR 25.194 10.326
169 T CAMK/PIM/PIM1 PPRERPHTSGHHGAG 14 5.965
209 T CAMK/MAPKAPK/MK5/MAPKAPK5 TTLRNTLTPATNDPR 12.545 6.633
38 T AGC/PDK1/PKH2 VAANKETTFQGLTIA 11 5.683
144 T CMGC/CDK/CDK5/CDK5 SVLHAPGTPVREGLR 24.148 7.867
158 T CMGC/MAPK/ERK/Erk2 RSHLAPRTPPLPPRE 23.991 4.61
209 T CMGC/CDK/CDK2/CDK2 TTLRNTLTPATNDPR 24.154 6.826
144 T CMGC/DYRK/DYRK2 SVLHAPGTPVREGLR 13.444 7.053
51 S AGC/RSK/MSK/RPS6KA5 IASGARESEKVFAQT 13.407 8.69
468 S AGC/PKC/PKCa/PRKCB QGRPLLNS******* 13.569 8.434
209 T CMGC/CDK/CDK2/CDC28 TTLRNTLTPATNDPR 11.778 9.411
181 T Other/TTK/TTK GAGEVRATAPSTVSP 61 47.968
80 T STE/STE20/MSN/MAP4K4 TAKLLQSTVKHNLNN 12 7
144 T CMGC/CDK/CDC2/CDK1 SVLHAPGTPVREGLR 12.698 4.168
51 S Other/AUR/AurC IASGARESEKVFAQT 12.667 6.434
144 T Atypical/PIKK/FRAP SVLHAPGTPVREGLR 17.889 8.145
305 S AGC/DMPK/ROCK MPDYFRQSGTYGSIT 14.242 6.326
20 S Other/NEK/NEK11 SRLVQQESGDCTGKL 14 8.933
185 T STE/STE20/MSN/TNIK VRATAPSTVSPYGPE 12 7
434 S Atypical/PIKK/ATR LSVEDMVSQMRVQRN 11.362 8.681
287 S Other/CDC7 PVLAVLASSSEIANQ 11.667 9.583
434 S AGC/PKC/PKCa/PRKCB LSVEDMVSQMRVQRN 14.672 8.434
209 T CMGC/MAPK/JNK/JNK2 TTLRNTLTPATNDPR 26.971 6.118
203 T Other/TTK/TTK ELSSRLTTLRNTLTP 54.182 47.968
6 S CAMK/CAMKL/QIK/SIK1 **MNLSLSDLHRQVS 11.312 2.597
318 T Other/TTK/TTK ITVESKMTQQVGLGD 57.727 47.968
261 Y TK/Csk/CTK TRTIACQYPLQSQLE 11 10
158 T CMGC/CDK/CDK2/CDC28 RSHLAPRTPPLPPRE 14.694 9.411
187 S CMGC/MAPK/JNK/JNK2 ATAPSTVSPYGPEAR 28.441 6.118
187 S CMGC/MAPK/p38/MAPK11 ATAPSTVSPYGPEAR 11.037 5.425
132 S CK1/CK1/CK1-D/CSNK1D SGARGHVSSHSHSVL 11.95 8.142
158 T CMGC/MAPK/ERK/Erk1 RSHLAPRTPPLPPRE 23.604 10.326
109 T Other/TTK/TTK SLRSDQMTLQDAKVL 50.455 47.968
51 S Other/CDC7 IASGARESEKVFAQT 12.667 9.583
217 Y TK/Trk/TRKA PATNDPRYLQACGGE 21.8 11.95
185 T STE/STE20/MSN/MINK1 VRATAPSTVSPYGPE 12 7
6 S CK1/VRK/VRK2 **MNLSLSDLHRQVS 20.75 4
144 T CMGC/MAPK/JNK/JNK2 SVLHAPGTPVREGLR 31.176 6.118
209 T CAMK/MAPKAPK/MK5 TTLRNTLTPATNDPR 12.545 6.633
378 T Other/TTK/TTK LVDQTAETKRNMYES 48.545 47.968
209 T CMGC/CDK/CDK5/CDK5 TTLRNTLTPATNDPR 14.531 7.867
144 T CMGC/CDK/CDK2/CDK2 SVLHAPGTPVREGLR 18.839 6.826

* Only the results whose Scores are more than 10 are listed here.

  • Click here to download the complete GPS results for this protein entry.
  • You can also go to the DOWNLOAD page to get the GPS results for all protein entries.

Pfam Domains (Experimental/Computational Results)

Top

id type start end
YopH_N Pfam 3 123
Y_phosphatase Pfam 224 459

Mutation (Experimental Results)

Top

POSITION WILD-TYPE AA MUTANT DISEASE/NOTES REFERENCE
Sorry. There is no result for this protein entry.

Pathway (Experimental Results)

Top

Pathway Accession Number Description
Sorry. There is no result for this protein entry.

Multiple Sequence Alignments (Computational Results)

Top

Protein Alignment (Computational Results)

Top