Comprehensive Information
Detailed Information (Experimental Results)
| Database ID | 15 |
| UniProt ID |
A1KWP2
|
| Name |
NleA1 protein
|
| Type |
Type III secretion system effector (T3SE)
|
| Gene Name |
nleA1
|
| Organism |
Escherichia coli
|
| Gene Ontology Terms |
-
|
| Function |
-
|
| Sequence |
MNIQPIVQSGITTQNNQHHHTEQTSPTQIPQSELPHGCETGFVVNIPEDIQQHIPECGETTALLGLIRDKGLLSGLDAYLAPHLEEGSAGKKALDMFGLFNVTQMALEIPSTVPGISGKYGVQMNIVKPDIHPTTGNYFLQLFPLHDEVGINFGALPGPLQKFLSQNPNPWFGVTAQVVRNHGIELPIVKTDNGWKLVGETPLTPEGPKANYTEEWVIRPGEFDLKYGSTPLQSTLGLEFGAHFKWDLDNPNTKYAILTNALANAAGAAGGYTLSQYTGTDAMLSPHVGSMAGQALGHAVQCYTPGLKPDTILWWAGTTLGLADLNKAETGEGRFTDYPRIWWHAREGAIFPNKEDIARATGADIRAMEEGIPVGQRHPNPEDVVIDIESNGLPHHNPSNHVDIFDIIQETRV
|
| Length |
413 amino acids
|
| Reference |
24391954
|
| IBS |
|
Protein Structure (Experimental Results)
| PDB Accession |
Method |
Resolution |
Chain |
Structure Review |
| Sorry. There is no result for this protein entry. |
Disorder Prediction (Computational Results)
| Start |
End |
Sequence |
| 284 |
287 |
LSPH |
| 369 |
385 |
EEGIPVGQRHPNPEDVV |
| 1 |
41 |
MNIQPIVQSGITTQNNQHHHTEQTSPTQIPQSELPHGCETG |
| 203 |
209 |
LTPEGPK |
| 290 |
292 |
SMA |
| 388 |
399 |
IESNGLPHHNPS |
| 84 |
92 |
LEEGSAGKK |
| 326 |
332 |
NKAETGE |
| 410 |
413 |
ETRV |
Disorder Picture (Computational Results)
Kinase-specific Phosphorylation Sites (Computational Results)
| Position |
Code |
Kinase |
Peptide |
Score |
Cutoff |
| 25 |
S |
CMGC/MAPK |
HHHTEQTSPTQIPQS |
11.577 |
4.55 |
| 25 |
S |
CMGC/MAPK/ERK/Erk1 |
HHHTEQTSPTQIPQS |
14.347 |
10.326 |
| 112 |
T |
STE/STE20/MSN/MINK1 |
MALEIPSTVPGISGK |
12 |
7 |
| 411 |
T |
AGC/GRK/GRK/GRK |
IFDIIQETRV***** |
13.444 |
6.878 |
| 275 |
S |
TKL/STKR/STKR1 |
AAGGYTLSQYTGTDA |
11.625 |
6.85 |
| 285 |
S |
CMGC/MAPK/JNK/JNK2 |
TGTDAMLSPHVGSMA |
39.294 |
6.118 |
| 330 |
T |
Other/NEK/NEK11 |
ADLNKAETGEGRFTD |
12.667 |
8.933 |
| 204 |
T |
CMGC/MAPK/ERK/Erk1 |
LVGETPLTPEGPKAN |
27.722 |
10.326 |
| 285 |
S |
CMGC/CDK/CDK5/PHO85 |
TGTDAMLSPHVGSMA |
11.056 |
7.061 |
| 204 |
T |
CMGC/CDK/CDK4 |
LVGETPLTPEGPKAN |
11.421 |
4.463 |
| 112 |
T |
STE/STE20/MSN/MAP4K4 |
MALEIPSTVPGISGK |
12 |
7 |
| 304 |
T |
CMGC/MAPK/ERK/Erk1 |
GHAVQCYTPGLKPDT |
13.903 |
10.326 |
| 25 |
S |
CMGC/MAPK/JNK/JNK2 |
HHHTEQTSPTQIPQS |
30.794 |
6.118 |
| 12 |
T |
Other/TTK/TTK |
PIVQSGITTQNNQHH |
56.182 |
47.968 |
| 13 |
T |
CK1 |
IVQSGITTQNNQHHH |
13.5 |
5.313 |
| 12 |
T |
CK1 |
PIVQSGITTQNNQHH |
12.049 |
5.313 |
| 411 |
T |
AGC/GRK/BARK/BARK1 |
IFDIIQETRV***** |
21.976 |
3.384 |
| 304 |
T |
CMGC/MAPK/JNK/JNK3 |
GHAVQCYTPGLKPDT |
12.062 |
6.781 |
| 399 |
S |
CAMK/MAPKAPK/MNK/MNK2 |
GLPHHNPSNHVDIFD |
13.286 |
6.869 |
| 112 |
T |
STE/STE20/PAKA/PAK3 |
MALEIPSTVPGISGK |
13.267 |
5.9 |
| 230 |
T |
CMGC/CDK/CDC2/CDK1 |
FDLKYGSTPLQSTLG |
11.869 |
4.168 |
| 285 |
S |
CMGC/CDK/CDK5 |
TGTDAMLSPHVGSMA |
15.909 |
6.616 |
| 235 |
T |
STE/STE20/MSN/MINK1 |
GSTPLQSTLGLEFGA |
11 |
7 |
| 204 |
T |
Other/TTK/TTK |
LVGETPLTPEGPKAN |
50.182 |
47.968 |
| 411 |
T |
Other/PEK |
IFDIIQETRV***** |
11.455 |
2.678 |
| 204 |
T |
CMGC/MAPK/JNK/JNK2 |
LVGETPLTPEGPKAN |
31.559 |
6.118 |
| 336 |
T |
STE/STE7/MEK3/MAP2K4 |
ETGEGRFTDYPRIWW |
11.6 |
0.017 |
| 111 |
S |
AGC/DMPK/ROCK |
QMALEIPSTVPGISG |
12.226 |
6.326 |
| 13 |
T |
CK1/VRK/VRK2 |
IVQSGITTQNNQHHH |
19.25 |
4 |
| 290 |
S |
Atypical/PDHK/PDHK |
MLSPHVGSMAGQALG |
11.025 |
2.805 |
| 318 |
T |
Atypical/PDHK/PDHK/PDK1 |
TILWWAGTTLGLADL |
22.378 |
2.714 |
| 230 |
T |
CMGC/MAPK/JNK/JNK2 |
FDLKYGSTPLQSTLG |
20.794 |
6.118 |
| 311 |
T |
STE/STE20/TAO/TAOK1 |
TPGLKPDTILWWAGT |
11 |
6.1 |
| 112 |
T |
STE/STE20/MSN/TNIK |
MALEIPSTVPGISGK |
12 |
7 |
| 204 |
T |
CMGC/MAPK |
LVGETPLTPEGPKAN |
13.607 |
4.55 |
| 411 |
T |
Other/PLK |
IFDIIQETRV***** |
12.981 |
8.093 |
| 204 |
T |
CMGC/CDK/CDK2/CDK2 |
LVGETPLTPEGPKAN |
15.537 |
6.826 |
| 201 |
T |
CMGC/MAPK/JNK/JNK2 |
GWKLVGETPLTPEGP |
30.029 |
6.118 |
| 201 |
T |
CMGC/CDK/CDK5/PHO85 |
GWKLVGETPLTPEGP |
11.222 |
7.061 |
| 285 |
S |
CAMK/MAPKAPK/MK5 |
TGTDAMLSPHVGSMA |
14.091 |
6.633 |
| 285 |
S |
CMGC/MAPK/p38 |
TGTDAMLSPHVGSMA |
11.081 |
4.309 |
| 204 |
T |
Atypical/PIKK/FRAP |
LVGETPLTPEGPKAN |
15.278 |
8.145 |
| 277 |
Y |
TK/Csk/CTK |
GGYTLSQYTGTDAML |
11 |
10 |
| 204 |
T |
CMGC/MAPK/ERK/Erk4 |
LVGETPLTPEGPKAN |
12.667 |
5.7 |
| 285 |
S |
CMGC/MAPK |
TGTDAMLSPHVGSMA |
11.677 |
4.55 |
| 235 |
T |
STE/STE20/MSN/TNIK |
GSTPLQSTLGLEFGA |
11 |
7 |
| 25 |
S |
CMGC/MAPK/ERK/Erk2 |
HHHTEQTSPTQIPQS |
12.323 |
4.61 |
| 60 |
T |
Other/TTK/TTK |
HIPECGETTALLGLI |
56.455 |
47.968 |
| 285 |
S |
CMGC/CDK/CDK2/CDC28 |
TGTDAMLSPHVGSMA |
12.194 |
9.411 |
| 411 |
T |
AGC/GRK/BARK |
IFDIIQETRV***** |
15.488 |
3.806 |
| 201 |
T |
CMGC/MAPK/ERK/Erk1 |
GWKLVGETPLTPEGP |
12.264 |
10.326 |
| 201 |
T |
Atypical/PIKK/FRAP |
GWKLVGETPLTPEGP |
18.167 |
8.145 |
| 285 |
S |
CAMK/MAPKAPK/MK5/MAPKAPK5 |
TGTDAMLSPHVGSMA |
14.091 |
6.633 |
| 285 |
S |
CMGC/MAPK/JNK/JNK3 |
TGTDAMLSPHVGSMA |
11.5 |
6.781 |
| 230 |
T |
CMGC/CDK/CDK5/PHO85 |
FDLKYGSTPLQSTLG |
12.111 |
7.061 |
| 204 |
T |
CMGC/MAPK/ERK/Erk2 |
LVGETPLTPEGPKAN |
20.677 |
4.61 |
| 361 |
T |
TKL/LISK/LIMK |
KEDIARATGADIRAM |
11 |
6 |
| 285 |
S |
CMGC/MAPK/p38/HOG1 |
TGTDAMLSPHVGSMA |
12.8 |
7.46 |
| 79 |
Y |
TK/Src/SrcB/HCK |
LLSGLDAYLAPHLEE |
12.233 |
6.378 |
| 230 |
T |
CMGC/MAPK/ERK/Erk1 |
FDLKYGSTPLQSTLG |
22.75 |
10.326 |
| 285 |
S |
CMGC/MAPK/ERK/Erk1 |
TGTDAMLSPHVGSMA |
18.257 |
10.326 |
| 204 |
T |
CMGC/DYRK/DYRK2 |
LVGETPLTPEGPKAN |
13.889 |
7.053 |
| 229 |
S |
CAMK/MAPKAPK/MNK/MNK1 |
EFDLKYGSTPLQSTL |
13 |
8.333 |
| 25 |
S |
CMGC/MAPK/ERK/FUS3 |
HHHTEQTSPTQIPQS |
11.667 |
3.833 |
| 255 |
Y |
TK/Csk/CSK |
LDNPNTKYAILTNAL |
11.593 |
9.741 |
| 361 |
T |
AGC/DMPK/ROCK |
KEDIARATGADIRAM |
19.903 |
6.326 |
| 229 |
S |
STE/STE-Unique/NIK |
EFDLKYGSTPLQSTL |
11 |
4.283 |
| 25 |
S |
CMGC/CDK/CDK2/CDC28 |
HHHTEQTSPTQIPQS |
15.583 |
9.411 |
| 25 |
S |
CMGC/MAPK/JNK/JNK3 |
HHHTEQTSPTQIPQS |
11.688 |
6.781 |
| 411 |
T |
AGC/GRK |
IFDIIQETRV***** |
11.914 |
6.103 |
| 27 |
T |
Other/TTK/TTK |
HTEQTSPTQIPQSEL |
49.273 |
47.968 |
| 9 |
S |
CK1/VRK/VRK2 |
NIQPIVQSGITTQNN |
14 |
4 |
| 304 |
T |
CMGC/CDK/CDK5/PHO85 |
GHAVQCYTPGLKPDT |
12.222 |
7.061 |
| 25 |
S |
CMGC/CDK/CDK5 |
HHHTEQTSPTQIPQS |
12.99 |
6.616 |
| 255 |
Y |
TK/Src/SrcA/FGR |
LDNPNTKYAILTNAL |
12.4 |
8.74 |
| 304 |
T |
CMGC/MAPK/JNK/JNK2 |
GHAVQCYTPGLKPDT |
26.294 |
6.118 |
| 204 |
T |
CMGC/CDK/CDK5 |
LVGETPLTPEGPKAN |
15.242 |
6.616 |
| 338 |
Y |
TK/Trk/TRKA |
GEGRFTDYPRIWWHA |
12.6 |
11.95 |
| 204 |
T |
CMGC/CDK/CDK5/CDK5 |
LVGETPLTPEGPKAN |
12.469 |
7.867 |
| 285 |
S |
CK1/TTBK/TTBK1 |
TGTDAMLSPHVGSMA |
12.125 |
5.133 |
| 230 |
T |
Atypical/PIKK/FRAP |
FDLKYGSTPLQSTLG |
16.5 |
8.145 |
| 361 |
T |
Other/AUR/AurB |
KEDIARATGADIRAM |
11.241 |
7.092 |
| 272 |
Y |
TK/Csk/CSK |
AAGAAGGYTLSQYTG |
12.926 |
9.741 |
| 201 |
T |
CMGC/CDK/CDC2/CDK1 |
GWKLVGETPLTPEGP |
12.995 |
4.168 |
| 235 |
T |
STE/STE20/MSN/MAP4K4 |
GSTPLQSTLGLEFGA |
11 |
7 |
| 12 |
T |
CK1/VRK/VRK2 |
PIVQSGITTQNNQHH |
18.25 |
4 |
| 201 |
T |
CMGC/CDK/CDK5/CDK5 |
GWKLVGETPLTPEGP |
17.679 |
7.867 |
| 134 |
T |
Other/NEK/NEK11 |
VKPDIHPTTGNYFLQ |
11 |
8.933 |
| 361 |
T |
TKL/LISK/LIMK/LIMK1 |
KEDIARATGADIRAM |
11 |
6 |
| 311 |
T |
STE/STE20/TAO |
TPGLKPDTILWWAGT |
11 |
6.1 |
| 204 |
T |
CMGC/CDK/CDK2/CDC28 |
LVGETPLTPEGPKAN |
11.528 |
9.411 |
| 304 |
T |
CK1/TTBK/TTBK1 |
GHAVQCYTPGLKPDT |
11 |
5.133 |
| 25 |
S |
CMGC/CDK/CDK5/CDK5 |
HHHTEQTSPTQIPQS |
14.049 |
7.867 |
| 304 |
T |
CMGC/CDK/CDK5/CDK5 |
GHAVQCYTPGLKPDT |
14.37 |
7.867 |
| 361 |
T |
STE/STE20/PAKA/PAK1 |
KEDIARATGADIRAM |
11.711 |
6.979 |
| 112 |
T |
Other/TTK/TTK |
MALEIPSTVPGISGK |
64.545 |
47.968 |
| 25 |
S |
CMGC/CDK/CDK2/CDK2 |
HHHTEQTSPTQIPQS |
14.611 |
6.826 |
| 411 |
T |
AGC/PKC/PKCa/PRKCA |
IFDIIQETRV***** |
12.485 |
5.842 |
| 134 |
T |
Other/TTK/TTK |
VKPDIHPTTGNYFLQ |
48.364 |
47.968 |
| 361 |
T |
Other/PEK |
KEDIARATGADIRAM |
15.682 |
2.678 |
* Only the results whose Scores are more than 10 are listed here.
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Pfam Domains (Experimental/Computational Results)
| id |
type |
start |
end |
| Sorry. There is no result for this protein entry. |
Mutation (Experimental Results)
| POSITION |
WILD-TYPE AA |
MUTANT |
DISEASE/NOTES |
REFERENCE |
| Sorry. There is no result for this protein entry. |
Pathway (Experimental Results)
| Pathway Accession Number |
Description |
| Sorry. There is no result for this protein entry. |
Multiple Sequence Alignments (Computational Results)
- Sorry. There is no multiple sequence alignment information for this entry.
Protein Alignment (Computational Results)
- Sorry. There is no ortholog information for this entry.
- Sorry. There is no alignment file for this entry.
