Comprehensive Information
Detailed Information (Experimental Results)
| Database ID | 16 |
| UniProt ID |
A1KWP3
|
| Name |
NleA2 protein
|
| Type |
Type III secretion system effector (T3SE)
|
| Gene Name |
nleA2
|
| Organism |
Escherichia coli
|
| Gene Ontology Terms |
-
|
| Function |
-
|
| Sequence |
MNIQPTIQSGITTQHNQHHHTEQTPPTQIPQSELPLGCQAGFVVNIPDDIQQHAPECGETTALLSLIKDKGLLSGLDAYIAPHLEEGSAGKKALDMFGLFNVTQMALEIPSTVPGISGKYGVQMNIVKPDIHPTTGNYFLQLFPLHDEVGINFGALPGPLQKFLSQNPNPWFGVTAQVVRNHGIELPIVKTDNGWKLVGETPLTPEGPKANYTEEWVIRPGELDLKYGSTPFQSTLGLEFGAHFKWDLDNPNTKYAVLTNALANAAGAAGGYTLSQYTGTNAMLSPHIGSMAGQALGHAVQCYTPGLKPDTILWWAGTTLGLADLNKAEFGVARFTDYPRIWWHAREGAIFPNKEDIARATGADIRAMEEGIPVGQRHPNPEDVVIDIESNGSPHHNPSNYVDTFDIIRETRV
|
| Length |
413 amino acids
|
| Reference |
26120140
|
| IBS |
|
Protein Structure (Experimental Results)
| PDB Accession |
Method |
Resolution |
Chain |
Structure Review |
| Sorry. There is no result for this protein entry. |
Disorder Prediction (Computational Results)
| Start |
End |
Sequence |
| 292 |
292 |
A |
| 1 |
39 |
MNIQPTIQSGITTQHNQHHHTEQTPPTQIPQSELPLGCQ |
| 409 |
413 |
RETRV |
| 203 |
209 |
LTPEGPK |
| 368 |
401 |
MEEGIPVGQRHPNPEDVVIDIESNGSPHHNPSNY |
| 86 |
91 |
EGSAGK |
Disorder Picture (Computational Results)
Kinase-specific Phosphorylation Sites (Computational Results)
| Position |
Code |
Kinase |
Peptide |
Score |
Cutoff |
| 404 |
T |
AGC/GRK/BARK/BARK1 |
NPSNYVDTFDIIRET |
22.69 |
3.384 |
| 393 |
S |
CMGC/MAPK/JNK/JNK2 |
IDIESNGSPHHNPSN |
24.853 |
6.118 |
| 393 |
S |
CMGC/MAPK/JNK/JNK3 |
IDIESNGSPHHNPSN |
11.688 |
6.781 |
| 285 |
S |
CAMK/MAPKAPK/MK5 |
TGTNAMLSPHIGSMA |
16.091 |
6.633 |
| 204 |
T |
CMGC/CDK/CDK4 |
LVGETPLTPEGPKAN |
11.421 |
4.463 |
| 230 |
T |
CMGC/CDK/CDK5/CDK5 |
LDLKYGSTPFQSTLG |
18.543 |
7.867 |
| 112 |
T |
STE/STE20/MSN/MAP4K4 |
MALEIPSTVPGISGK |
12 |
7 |
| 285 |
S |
CMGC/MAPK/JNK/JNK3 |
TGTNAMLSPHIGSMA |
11.5 |
6.781 |
| 204 |
T |
CMGC/MAPK/ERK/Erk4 |
LVGETPLTPEGPKAN |
12.667 |
5.7 |
| 6 |
T |
Other/PLK |
**MNIQPTIQSGITT |
13.175 |
8.093 |
| 6 |
T |
CK1/VRK/VRK2 |
**MNIQPTIQSGITT |
24 |
4 |
| 311 |
T |
STE/STE20/TAO |
TPGLKPDTILWWAGT |
11 |
6.1 |
| 411 |
T |
AGC/PKC/PKCa/PRKCA |
TFDIIRETRV***** |
12.995 |
5.842 |
| 393 |
S |
CMGC/MAPK/ERK/FUS3 |
IDIESNGSPHHNPSN |
11.667 |
3.833 |
| 411 |
T |
AGC/GRK/GRK/GRK |
TFDIIRETRV***** |
12.278 |
6.878 |
| 201 |
T |
CMGC/CDK/CDC2/CDK1 |
GWKLVGETPLTPEGP |
12.995 |
4.168 |
| 393 |
S |
CK1/TTBK/TTBK1 |
IDIESNGSPHHNPSN |
15.75 |
5.133 |
| 285 |
S |
CMGC/MAPK/ERK/Erk1 |
TGTNAMLSPHIGSMA |
17.729 |
10.326 |
| 393 |
S |
CMGC/CDK/CDK5 |
IDIESNGSPHHNPSN |
15.515 |
6.616 |
| 304 |
T |
CK1/TTBK/TTBK1 |
GHAVQCYTPGLKPDT |
11 |
5.133 |
| 404 |
T |
STE/STE20/TAO |
NPSNYVDTFDIIRET |
17 |
6.1 |
| 201 |
T |
Atypical/PIKK/FRAP |
GWKLVGETPLTPEGP |
18.167 |
8.145 |
| 401 |
Y |
TK/Eph/EphA4 |
PHHNPSNYVDTFDII |
13.75 |
6.6 |
| 112 |
T |
STE/STE20/MSN/MINK1 |
MALEIPSTVPGISGK |
12 |
7 |
| 134 |
T |
Other/TTK/TTK |
VKPDIHPTTGNYFLQ |
48.364 |
47.968 |
| 204 |
T |
Atypical/PIKK/FRAP |
LVGETPLTPEGPKAN |
15.278 |
8.145 |
| 229 |
S |
STE/STE-Unique/NIK |
ELDLKYGSTPFQSTL |
11.667 |
4.283 |
| 285 |
S |
CAMK/MAPKAPK/MK5/MAPKAPK5 |
TGTNAMLSPHIGSMA |
16.091 |
6.633 |
| 304 |
T |
CMGC/CDK/CDK5/CDK5 |
GHAVQCYTPGLKPDT |
14.37 |
7.867 |
| 112 |
T |
STE/STE20/MSN/TNIK |
MALEIPSTVPGISGK |
12 |
7 |
| 9 |
S |
CK1/VRK/VRK2 |
NIQPTIQSGITTQHN |
13.75 |
4 |
| 361 |
T |
Other/AUR/AurB |
KEDIARATGADIRAM |
11.241 |
7.092 |
| 24 |
T |
CMGC/CDK/CDK5/CDK5 |
QHHHTEQTPPTQIPQ |
12.481 |
7.867 |
| 201 |
T |
CMGC/MAPK/ERK/Erk1 |
GWKLVGETPLTPEGP |
12.264 |
10.326 |
| 285 |
S |
CMGC/MAPK/JNK/JNK2 |
TGTNAMLSPHIGSMA |
38.676 |
6.118 |
| 277 |
Y |
TK/Csk/CTK |
GGYTLSQYTGTNAML |
11 |
10 |
| 12 |
T |
Other/TTK/TTK |
PTIQSGITTQHNQHH |
56.182 |
47.968 |
| 24 |
T |
Atypical/PIKK/FRAP |
QHHHTEQTPPTQIPQ |
13.361 |
8.145 |
| 235 |
T |
STE/STE20/MSN/MAP4K4 |
GSTPFQSTLGLEFGA |
11 |
7 |
| 311 |
T |
STE/STE20/TAO/TAOK1 |
TPGLKPDTILWWAGT |
11 |
6.1 |
| 338 |
Y |
TK/Csk/CSK |
GVARFTDYPRIWWHA |
11.704 |
9.741 |
| 361 |
T |
STE/STE20/PAKA/PAK1 |
KEDIARATGADIRAM |
11.711 |
6.979 |
| 393 |
S |
CMGC/CDK/CDK2/CDC28 |
IDIESNGSPHHNPSN |
14.806 |
9.411 |
| 304 |
T |
CMGC/MAPK/ERK/Erk1 |
GHAVQCYTPGLKPDT |
13.903 |
10.326 |
| 285 |
S |
CMGC/CDK/CDK5/PHO85 |
TGTNAMLSPHIGSMA |
11.167 |
7.061 |
| 24 |
T |
CMGC/MAPK/ERK/Erk1 |
QHHHTEQTPPTQIPQ |
13.312 |
10.326 |
| 204 |
T |
CMGC/MAPK/ERK/Erk2 |
LVGETPLTPEGPKAN |
20.677 |
4.61 |
| 404 |
T |
AGC/DMPK/ROCK |
NPSNYVDTFDIIRET |
11.435 |
6.326 |
| 393 |
S |
Other/Other-Unique/KIS |
IDIESNGSPHHNPSN |
12.833 |
6.008 |
| 229 |
S |
CAMK/MAPKAPK/MNK/MNK1 |
ELDLKYGSTPFQSTL |
13 |
8.333 |
| 204 |
T |
CMGC/CDK/CDK2/CDC28 |
LVGETPLTPEGPKAN |
11.528 |
9.411 |
| 13 |
T |
CK1 |
TIQSGITTQHNQHHH |
14.646 |
5.313 |
| 290 |
S |
Atypical/PDHK/PDHK |
MLSPHIGSMAGQALG |
11.025 |
2.805 |
| 230 |
T |
CMGC/MAPK/ERK/Erk1 |
LDLKYGSTPFQSTLG |
23.75 |
10.326 |
| 411 |
T |
AGC/DMPK/ROCK |
TFDIIRETRV***** |
17.548 |
6.326 |
| 404 |
T |
AGC/GRK/BARK |
NPSNYVDTFDIIRET |
12.558 |
3.806 |
| 393 |
S |
CMGC/DYRK/DYRK2 |
IDIESNGSPHHNPSN |
11.611 |
7.053 |
| 399 |
S |
CAMK/MAPKAPK/MNK/MNK2 |
GSPHHNPSNYVDTFD |
13.286 |
6.869 |
| 201 |
T |
CMGC/CDK/CDK5/CDK5 |
GWKLVGETPLTPEGP |
17.679 |
7.867 |
| 304 |
T |
CMGC/MAPK/JNK/JNK2 |
GHAVQCYTPGLKPDT |
26.294 |
6.118 |
| 404 |
T |
AGC/PDK1/PKH2 |
NPSNYVDTFDIIRET |
13.333 |
5.683 |
| 111 |
S |
AGC/DMPK/ROCK |
QMALEIPSTVPGISG |
12.226 |
6.326 |
| 24 |
T |
CMGC/CDK/CDC2/CDK1 |
QHHHTEQTPPTQIPQ |
14.357 |
4.168 |
| 24 |
T |
CMGC/CDK/CDK2/CDC28 |
QHHHTEQTPPTQIPQ |
13.611 |
9.411 |
| 204 |
T |
CMGC/MAPK/JNK/JNK2 |
LVGETPLTPEGPKAN |
31.559 |
6.118 |
| 399 |
S |
Other/PLK |
GSPHHNPSNYVDTFD |
12 |
8.093 |
| 393 |
S |
CMGC/MAPK/ERK/Erk1 |
IDIESNGSPHHNPSN |
11.785 |
10.326 |
| 235 |
T |
STE/STE20/MSN/MINK1 |
GSTPFQSTLGLEFGA |
11 |
7 |
| 12 |
T |
CK1 |
PTIQSGITTQHNQHH |
13.819 |
5.313 |
| 204 |
T |
CMGC/CDK/CDK2/CDK2 |
LVGETPLTPEGPKAN |
15.537 |
6.826 |
| 285 |
S |
CMGC/MAPK/p38/HOG1 |
TGTNAMLSPHIGSMA |
12.8 |
7.46 |
| 338 |
Y |
TK/Trk/TRKA |
GVARFTDYPRIWWHA |
12.6 |
11.95 |
| 230 |
T |
CMGC/CDK/CDK5 |
LDLKYGSTPFQSTLG |
11.788 |
6.616 |
| 79 |
Y |
TK/Eph/EphB1 |
LLSGLDAYIAPHLEE |
11.333 |
7.967 |
| 411 |
T |
AGC/GRK/BARK/BARK1 |
TFDIIRETRV***** |
21.976 |
3.384 |
| 112 |
T |
Other/TTK/TTK |
MALEIPSTVPGISGK |
64.545 |
47.968 |
| 24 |
T |
CMGC/MAPK/ERK/Erk2 |
QHHHTEQTPPTQIPQ |
13.181 |
4.61 |
| 404 |
T |
STE/STE20/YSK |
NPSNYVDTFDIIRET |
12 |
6.05 |
| 361 |
T |
AGC/DMPK/ROCK |
KEDIARATGADIRAM |
19.903 |
6.326 |
| 60 |
T |
Other/TTK/TTK |
HAPECGETTALLSLI |
56.455 |
47.968 |
| 411 |
T |
Other/PEK |
TFDIIRETRV***** |
11.273 |
2.678 |
| 235 |
T |
STE/STE20/MSN/TNIK |
GSTPFQSTLGLEFGA |
11 |
7 |
| 112 |
T |
STE/STE20/PAKA/PAK3 |
MALEIPSTVPGISGK |
13.267 |
5.9 |
| 285 |
S |
CMGC/MAPK |
TGTNAMLSPHIGSMA |
11.808 |
4.55 |
| 27 |
T |
Atypical/PIKK/FRAP |
HTEQTPPTQIPQSEL |
13.028 |
8.145 |
| 13 |
T |
CK1/VRK/VRK2 |
TIQSGITTQHNQHHH |
18.5 |
4 |
| 204 |
T |
CMGC/CDK/CDK5 |
LVGETPLTPEGPKAN |
15.242 |
6.616 |
| 285 |
S |
CK1/TTBK/TTBK1 |
TGTNAMLSPHIGSMA |
12.125 |
5.133 |
| 79 |
Y |
TK/PDGFR/KIT |
LLSGLDAYIAPHLEE |
11.625 |
8.15 |
| 204 |
T |
Other/TTK/TTK |
LVGETPLTPEGPKAN |
50.182 |
47.968 |
| 361 |
T |
TKL/LISK/LIMK |
KEDIARATGADIRAM |
11 |
6 |
| 204 |
T |
CMGC/CDK/CDK5/CDK5 |
LVGETPLTPEGPKAN |
12.469 |
7.867 |
| 201 |
T |
CMGC/MAPK/JNK/JNK2 |
GWKLVGETPLTPEGP |
30.029 |
6.118 |
| 12 |
T |
CK1/VRK/VRK2 |
PTIQSGITTQHNQHH |
19.75 |
4 |
| 404 |
T |
Atypical/PDHK/PDHK |
NPSNYVDTFDIIRET |
15.8 |
2.805 |
| 255 |
Y |
TK/Src/SrcA/FGR |
LDNPNTKYAVLTNAL |
12.4 |
8.74 |
| 24 |
T |
CMGC/MAPK/JNK/JNK2 |
QHHHTEQTPPTQIPQ |
32.206 |
6.118 |
| 411 |
T |
AGC/GRK/BARK |
TFDIIRETRV***** |
15.488 |
3.806 |
| 411 |
T |
AGC/PKC/PKCa/PRKCB |
TFDIIRETRV***** |
13.259 |
8.434 |
| 304 |
T |
CMGC/MAPK/JNK/JNK3 |
GHAVQCYTPGLKPDT |
12.062 |
6.781 |
| 79 |
Y |
TK/Src/SrcB/HCK |
LLSGLDAYIAPHLEE |
13.4 |
6.378 |
| 134 |
T |
Other/NEK/NEK11 |
VKPDIHPTTGNYFLQ |
11 |
8.933 |
| 201 |
T |
CMGC/CDK/CDK5/PHO85 |
GWKLVGETPLTPEGP |
11.222 |
7.061 |
| 204 |
T |
CMGC/MAPK/ERK/Erk1 |
LVGETPLTPEGPKAN |
27.722 |
10.326 |
| 285 |
S |
CMGC/CDK/CDK5 |
TGTNAMLSPHIGSMA |
14.535 |
6.616 |
| 255 |
Y |
TK/Csk/CSK |
LDNPNTKYAVLTNAL |
12.667 |
9.741 |
| 230 |
T |
CMGC/CDK/CDK5/PHO85 |
LDLKYGSTPFQSTLG |
13.889 |
7.061 |
| 393 |
S |
CMGC/CDK/CDK2/CDK2 |
IDIESNGSPHHNPSN |
19.765 |
6.826 |
| 230 |
T |
CMGC/MAPK/JNK/JNK2 |
LDLKYGSTPFQSTLG |
20.794 |
6.118 |
| 361 |
T |
Other/PEK |
KEDIARATGADIRAM |
15.682 |
2.678 |
| 27 |
T |
Other/TTK/TTK |
HTEQTPPTQIPQSEL |
49.273 |
47.968 |
| 304 |
T |
CMGC/CDK/CDK5/PHO85 |
GHAVQCYTPGLKPDT |
12.222 |
7.061 |
| 12 |
T |
Other/PLK |
PTIQSGITTQHNQHH |
12.377 |
8.093 |
| 318 |
T |
Atypical/PDHK/PDHK/PDK1 |
TILWWAGTTLGLADL |
23.27 |
2.714 |
| 404 |
T |
STE/STE20/TAO/TAOK1 |
NPSNYVDTFDIIRET |
17 |
6.1 |
| 204 |
T |
CMGC/MAPK |
LVGETPLTPEGPKAN |
13.607 |
4.55 |
| 404 |
T |
AGC/GRK |
NPSNYVDTFDIIRET |
17.655 |
6.103 |
| 204 |
T |
CMGC/DYRK/DYRK2 |
LVGETPLTPEGPKAN |
13.889 |
7.053 |
| 285 |
S |
CMGC/CDK/CDK2/CDC28 |
TGTNAMLSPHIGSMA |
11 |
9.411 |
| 361 |
T |
TKL/LISK/LIMK/LIMK1 |
KEDIARATGADIRAM |
11 |
6 |
| 24 |
T |
CMGC/CDK/CDK4/CDK6 |
QHHHTEQTPPTQIPQ |
11 |
3.967 |
| 393 |
S |
CMGC/CDK/CDK5/CDK5 |
IDIESNGSPHHNPSN |
16.79 |
7.867 |
* Only the results whose Scores are more than 10 are listed here.
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Pfam Domains (Experimental/Computational Results)
| id |
type |
start |
end |
| Sorry. There is no result for this protein entry. |
Mutation (Experimental Results)
| POSITION |
WILD-TYPE AA |
MUTANT |
DISEASE/NOTES |
REFERENCE |
| Sorry. There is no result for this protein entry. |
Pathway (Experimental Results)
| Pathway Accession Number |
Description |
| Sorry. There is no result for this protein entry. |
Multiple Sequence Alignments (Computational Results)
- Sorry. There is no multiple sequence alignment information for this entry.
Protein Alignment (Computational Results)
- Sorry. There is no ortholog information for this entry.
- Sorry. There is no alignment file for this entry.
