Comprehensive Information
Detailed Information (Experimental Results)
| Database ID | 19 |
| UniProt ID |
A1KWP6
|
| Name |
NleA5 protein
|
| Type |
Type III secretion system effector (T3SE)
|
| Gene Name |
nleA5
|
| Organism |
Escherichia coli
|
| Gene Ontology Terms |
-
|
| Function |
-
|
| Sequence |
MNIQPTIQSGITTQHNQHHHTEQTPPTQIPQSELPLGCQAGFVVNIPDDIQQHAPECGETTALLSLIKDKGLLSGLDAYIAPHLEEGSAGKKALDMFGLFNVTQMALEIPSSTVPGISGKYGVQLNIVKPDIHPTSGNYFLQIFPLHDEIGINFKDLPGPLKNALSNSNIPTTVSTAASTIASATTSTVTTASKDLIPWFGLTAQVVRNHGVELPIVKTEKGWKLVGETPLTPDGPKANYTEEWVIRPGEVDFKYGTSPLQATLGLEFGAHFKWDLDNSNTKYAVLTNAAANALGAAGGFAVSKIPGVDSMLAPHIGAMVGQAAGHAIQCNTPGLKPDTILWWAGTTLGLADLNKAETGEARFTDYPRIWWHAREGAIFPNKEDIARATGADIRAMEEGVPVDHRHPHPEDVVIDIESSPHNNPSNYVDTVDIIRETRV
|
| Length |
439 amino acids
|
| Reference |
26120140
|
| IBS |
|
Protein Structure (Experimental Results)
| PDB Accession |
Method |
Resolution |
Chain |
Structure Review |
| Sorry. There is no result for this protein entry. |
Disorder Prediction (Computational Results)
| Start |
End |
Sequence |
| 232 |
237 |
TPDGPK |
| 394 |
439 |
RAMEEGVPVDHRHPHPEDVVIDIESSPHNNPSNYVDTVDIIRETRV |
| 161 |
190 |
LKNALSNSNIPTTVSTAASTIASATTSTVT |
| 1 |
39 |
MNIQPTIQSGITTQHNQHHHTEQTPPTQIPQSELPLGCQ |
| 86 |
91 |
EGSAGK |
| 355 |
358 |
KAET |
Disorder Picture (Computational Results)
Kinase-specific Phosphorylation Sites (Computational Results)
| Position |
Code |
Kinase |
Peptide |
Score |
Cutoff |
| 180 |
T |
CK1/CK1/CK1-D/CK1e |
TVSTAASTIASATTS |
11.647 |
4.55 |
| 188 |
T |
Other/TTK/TTK |
IASATTSTVTTASKD |
51.182 |
47.968 |
| 279 |
S |
AGC/GRK/GRK/GRK |
FKWDLDNSNTKYAVL |
11 |
6.878 |
| 79 |
Y |
TK/Eph/EphB1 |
LLSGLDAYIAPHLEE |
11.333 |
7.967 |
| 232 |
T |
CMGC/DYRK/DYRK2 |
LVGETPLTPDGPKAN |
13.889 |
7.053 |
| 258 |
S |
CMGC/CDK/CDK5/PHO85 |
VDFKYGTSPLQATLG |
12.111 |
7.061 |
| 180 |
T |
STE/STE20/MSN/MAP4K4 |
TVSTAASTIASATTS |
13 |
7 |
| 232 |
T |
Other/TTK/TTK |
LVGETPLTPDGPKAN |
50.182 |
47.968 |
| 24 |
T |
CMGC/MAPK/ERK/Erk1 |
QHHHTEQTPPTQIPQ |
13.312 |
10.326 |
| 112 |
S |
CAMK/MAPKAPK/MNK/MNK1 |
MALEIPSSTVPGISG |
11 |
8.333 |
| 437 |
T |
Other/PEK |
TVDIIRETRV***** |
11.455 |
2.678 |
| 419 |
S |
CMGC/MAPK/JNK/JNK2 |
VVIDIESSPHNNPSN |
25.324 |
6.118 |
| 437 |
T |
AGC/GRK/BARK |
TVDIIRETRV***** |
15.488 |
3.806 |
| 430 |
T |
AGC/GRK/BARK/BARK1 |
NPSNYVDTVDIIRET |
22.69 |
3.384 |
| 419 |
S |
CMGC/CDK/CDK2/CDC28 |
VVIDIESSPHNNPSN |
17.861 |
9.411 |
| 176 |
T |
Other/PLK |
NIPTTVSTAASTIAS |
12.344 |
8.093 |
| 12 |
T |
CK1 |
PTIQSGITTQHNQHH |
13.819 |
5.313 |
| 13 |
T |
CK1/VRK/VRK2 |
TIQSGITTQHNQHHH |
18.5 |
4 |
| 339 |
T |
STE/STE20/TAO |
TPGLKPDTILWWAGT |
11 |
6.1 |
| 258 |
S |
CMGC/MAPK/ERK/Erk1 |
VDFKYGTSPLQATLG |
16.549 |
10.326 |
| 425 |
S |
Other/PLK |
SSPHNNPSNYVDTVD |
18.974 |
8.093 |
| 60 |
T |
Other/TTK/TTK |
HAPECGETTALLSLI |
56.455 |
47.968 |
| 168 |
S |
CAMK/MAPKAPK/MNK/MNK2 |
LKNALSNSNIPTTVS |
16.286 |
6.869 |
| 113 |
T |
STE/STE20/PAKA/PAK3 |
ALEIPSSTVPGISGK |
13 |
5.9 |
| 191 |
T |
Other/TTK/TTK |
ATTSTVTTASKDLIP |
57.182 |
47.968 |
| 258 |
S |
CMGC/MAPK/JNK/JNK2 |
VDFKYGTSPLQATLG |
22.412 |
6.118 |
| 27 |
T |
Atypical/PIKK/FRAP |
HTEQTPPTQIPQSEL |
13.028 |
8.145 |
| 27 |
T |
Other/TTK/TTK |
HTEQTPPTQIPQSEL |
49.273 |
47.968 |
| 183 |
S |
CAMK/RAD53/DUN1 |
TAASTIASATTSTVT |
11 |
6.017 |
| 232 |
T |
CMGC/CDK/CDK2/CDC28 |
LVGETPLTPDGPKAN |
12.194 |
9.411 |
| 437 |
T |
AGC/GRK/BARK/BARK1 |
TVDIIRETRV***** |
21.976 |
3.384 |
| 419 |
S |
CMGC/CDK/CDK2/CDK2 |
VVIDIESSPHNNPSN |
18.617 |
6.826 |
| 258 |
S |
Atypical/PIKK/FRAP |
VDFKYGTSPLQATLG |
11.333 |
8.145 |
| 24 |
T |
CMGC/CDK/CDK2/CDC28 |
QHHHTEQTPPTQIPQ |
13.611 |
9.411 |
| 113 |
T |
STE/STE20/MSN/TNIK |
ALEIPSSTVPGISGK |
12 |
7 |
| 332 |
T |
CK1/TTBK/TTBK1 |
GHAIQCNTPGLKPDT |
13.625 |
5.133 |
| 283 |
Y |
TK/Csk/CSK |
LDNSNTKYAVLTNAA |
12 |
9.741 |
| 229 |
T |
CMGC/MAPK/JNK/JNK2 |
GWKLVGETPLTPDGP |
30.029 |
6.118 |
| 419 |
S |
CMGC/CDK/CDK5 |
VVIDIESSPHNNPSN |
12.394 |
6.616 |
| 258 |
S |
CMGC/CDK/CDK5/CDK5 |
VDFKYGTSPLQATLG |
13.938 |
7.867 |
| 24 |
T |
CMGC/MAPK/ERK/Erk2 |
QHHHTEQTPPTQIPQ |
13.181 |
4.61 |
| 419 |
S |
CMGC/DYRK/DYRK2 |
VVIDIESSPHNNPSN |
11.944 |
7.053 |
| 24 |
T |
CMGC/CDK/CDC2/CDK1 |
QHHHTEQTPPTQIPQ |
14.357 |
4.168 |
| 172 |
T |
Atypical/PDHK/PDHK/PDK1 |
LSNSNIPTTVSTAAS |
12.486 |
2.714 |
| 332 |
T |
CMGC/MAPK/ERK/Erk1 |
GHAIQCNTPGLKPDT |
14.764 |
10.326 |
| 168 |
S |
TKL/MLK |
LKNALSNSNIPTTVS |
16.16 |
7.138 |
| 24 |
T |
CMGC/MAPK/JNK/JNK2 |
QHHHTEQTPPTQIPQ |
32.206 |
6.118 |
| 9 |
S |
CK1/VRK/VRK2 |
NIQPTIQSGITTQHN |
13.75 |
4 |
| 188 |
T |
STE/STE20/MSN/MINK1 |
IASATTSTVTTASKD |
12 |
7 |
| 168 |
S |
AGC/GRK/GRK/GRK |
LKNALSNSNIPTTVS |
12.167 |
6.878 |
| 12 |
T |
Other/PLK |
PTIQSGITTQHNQHH |
12.377 |
8.093 |
| 437 |
T |
AGC/PKC/PKCa/PRKCB |
TVDIIRETRV***** |
13.259 |
8.434 |
| 229 |
T |
CMGC/MAPK/ERK/Erk1 |
GWKLVGETPLTPDGP |
11.965 |
10.326 |
| 232 |
T |
CMGC/CDK/CDK5 |
LVGETPLTPDGPKAN |
14.253 |
6.616 |
| 229 |
T |
CMGC/CDK/CDC2/CDK1 |
GWKLVGETPLTPDGP |
12.344 |
4.168 |
| 232 |
T |
CMGC/CDK/CDK5/CDK5 |
LVGETPLTPDGPKAN |
12.864 |
7.867 |
| 339 |
T |
STE/STE20/TAO/TAOK1 |
TPGLKPDTILWWAGT |
11 |
6.1 |
| 187 |
S |
TKL/STKR/STKR1 |
TIASATTSTVTTASK |
11.125 |
6.85 |
| 188 |
T |
STE/STE20/MSN/TNIK |
IASATTSTVTTASKD |
12 |
7 |
| 389 |
T |
AGC/DMPK/ROCK |
KEDIARATGADIRAM |
18.032 |
6.326 |
| 193 |
S |
Other/CDC7/CDC7 |
TSTVTTASKDLIPWF |
11 |
9.583 |
| 172 |
T |
AGC/GRK/GRK/GRK |
LSNSNIPTTVSTAAS |
12.389 |
6.878 |
| 332 |
T |
CMGC/CDK/CDK5/PHO85 |
GHAIQCNTPGLKPDT |
12.778 |
7.061 |
| 437 |
T |
AGC/DMPK/ROCK |
TVDIIRETRV***** |
18.226 |
6.326 |
| 430 |
T |
AGC/GRK/BARK |
NPSNYVDTVDIIRET |
13.233 |
3.806 |
| 185 |
T |
CK1/CK1/CK1-D/CSNK1D |
ASTIASATTSTVTTA |
11.55 |
8.142 |
| 229 |
T |
CK1/TTBK |
GWKLVGETPLTPDGP |
12.5 |
3.877 |
| 232 |
T |
CMGC/MAPK |
LVGETPLTPDGPKAN |
13.303 |
4.55 |
| 24 |
T |
CMGC/CDK/CDK4/CDK6 |
QHHHTEQTPPTQIPQ |
11 |
3.967 |
| 419 |
S |
CMGC/CDK/CDK5/PHO85 |
VVIDIESSPHNNPSN |
11.944 |
7.061 |
| 113 |
T |
STE/STE20/MSN/MINK1 |
ALEIPSSTVPGISGK |
12 |
7 |
| 79 |
Y |
TK/PDGFR/KIT |
LLSGLDAYIAPHLEE |
11.625 |
8.15 |
| 346 |
T |
Atypical/PDHK/PDHK/PDK1 |
TILWWAGTTLGLADL |
23.027 |
2.714 |
| 79 |
Y |
TK/Src/SrcB/HCK |
LLSGLDAYIAPHLEE |
13.4 |
6.378 |
| 185 |
T |
STE/STE20/MST/MST1 |
ASTIASATTSTVTTA |
45.484 |
2.612 |
| 188 |
T |
STE/STE20/MSN/MAP4K4 |
IASATTSTVTTASKD |
12 |
7 |
| 418 |
S |
Other/CDC7/CDC7 |
DVVIDIESSPHNNPS |
11.667 |
9.583 |
| 166 |
S |
AGC/RSK/RSKp90/RPS6KA3 |
GPLKNALSNSNIPTT |
12.059 |
8.112 |
| 229 |
T |
CMGC/CDK/CDK5/CDK5 |
GWKLVGETPLTPDGP |
18.593 |
7.867 |
| 389 |
T |
TKL/LISK/LIMK/LIMK1 |
KEDIARATGADIRAM |
11 |
6 |
| 183 |
S |
Other/CDC7/CDC7 |
TAASTIASATTSTVT |
15.333 |
9.583 |
| 279 |
S |
CAMK/MAPKAPK/MNK/MNK2 |
FKWDLDNSNTKYAVL |
13.286 |
6.869 |
| 24 |
T |
CMGC/CDK/CDK5/CDK5 |
QHHHTEQTPPTQIPQ |
12.481 |
7.867 |
| 180 |
T |
STE/STE20/MSN/TNIK |
TVSTAASTIASATTS |
13 |
7 |
| 6 |
T |
Other/PLK |
**MNIQPTIQSGITT |
13.175 |
8.093 |
| 437 |
T |
AGC/PKC/PKCa/PRKCA |
TVDIIRETRV***** |
12.995 |
5.842 |
| 364 |
T |
STE/STE7/MEK3/MAP2K4 |
ETGEARFTDYPRIWW |
12.4 |
0.017 |
| 332 |
T |
CMGC/MAPK/JNK/JNK3 |
GHAIQCNTPGLKPDT |
12.062 |
6.781 |
| 113 |
T |
STE/STE20/MSN/MAP4K4 |
ALEIPSSTVPGISGK |
12 |
7 |
| 183 |
S |
Other/CDC7 |
TAASTIASATTSTVT |
15.333 |
9.583 |
| 193 |
S |
Other/CDC7 |
TSTVTTASKDLIPWF |
11 |
9.583 |
| 232 |
T |
Atypical/PIKK/FRAP |
LVGETPLTPDGPKAN |
15.361 |
8.145 |
| 13 |
T |
CK1 |
TIQSGITTQHNQHHH |
14.646 |
5.313 |
| 12 |
T |
Other/TTK/TTK |
PTIQSGITTQHNQHH |
56.182 |
47.968 |
| 232 |
T |
CMGC/CDK/CDK2/CDK2 |
LVGETPLTPDGPKAN |
11.067 |
6.826 |
| 24 |
T |
Atypical/PIKK/FRAP |
QHHHTEQTPPTQIPQ |
13.361 |
8.145 |
| 258 |
S |
CMGC/MAPK/ERK/FUS3 |
VDFKYGTSPLQATLG |
11.667 |
3.833 |
| 180 |
T |
STE/STE20/MSN/MINK1 |
TVSTAASTIASATTS |
13 |
7 |
| 172 |
T |
Other/TTK/TTK |
LSNSNIPTTVSTAAS |
49.636 |
47.968 |
| 186 |
T |
AGC/GRK/GRK/GRK |
STIASATTSTVTTAS |
12.556 |
6.878 |
| 229 |
T |
CMGC/CDK/CDK5/PHO85 |
GWKLVGETPLTPDGP |
11.222 |
7.061 |
| 232 |
T |
CMGC/MAPK/ERK/Erk2 |
LVGETPLTPDGPKAN |
19.429 |
4.61 |
| 419 |
S |
CMGC/MAPK/ERK/FUS3 |
VVIDIESSPHNNPSN |
11.333 |
3.833 |
| 229 |
T |
Atypical/PIKK/FRAP |
GWKLVGETPLTPDGP |
15.139 |
8.145 |
| 6 |
T |
CK1/VRK/VRK2 |
**MNIQPTIQSGITT |
24 |
4 |
| 332 |
T |
CMGC/CDK/CDK5/CDK5 |
GHAIQCNTPGLKPDT |
14.222 |
7.867 |
| 366 |
Y |
TK/Csk/CSK |
GEARFTDYPRIWWHA |
11.148 |
9.741 |
| 12 |
T |
CK1/VRK/VRK2 |
PTIQSGITTQHNQHH |
19.75 |
4 |
| 179 |
S |
CAMK/MAPKAPK/MNK/MNK1 |
TTVSTAASTIASATT |
11.5 |
8.333 |
| 389 |
T |
STE/STE20/PAKA/PAK1 |
KEDIARATGADIRAM |
11.711 |
6.979 |
| 358 |
T |
Other/NEK/NEK11 |
ADLNKAETGEARFTD |
14.333 |
8.933 |
| 176 |
T |
Other/TTK/TTK |
NIPTTVSTAASTIAS |
48 |
47.968 |
| 389 |
T |
TKL/LISK/LIMK |
KEDIARATGADIRAM |
11 |
6 |
| 425 |
S |
CAMK/MAPKAPK/MNK/MNK2 |
SSPHNNPSNYVDTVD |
13.286 |
6.869 |
| 258 |
S |
CMGC/CDK/CDK5 |
VDFKYGTSPLQATLG |
12.697 |
6.616 |
| 366 |
Y |
TK/Trk/TRKA |
GEARFTDYPRIWWHA |
12.6 |
11.95 |
| 232 |
T |
CMGC/MAPK/JNK/JNK2 |
LVGETPLTPDGPKAN |
31.559 |
6.118 |
| 437 |
T |
AGC/GRK/GRK/GRK |
TVDIIRETRV***** |
12.278 |
6.878 |
| 185 |
T |
TKL/STKR/STKR1 |
ASTIASATTSTVTTA |
13.625 |
6.85 |
| 389 |
T |
Other/AUR/AurB |
KEDIARATGADIRAM |
11.241 |
7.092 |
| 419 |
S |
CMGC/MAPK/ERK/Erk1 |
VVIDIESSPHNNPSN |
18.597 |
10.326 |
| 418 |
S |
Other/CDC7 |
DVVIDIESSPHNNPS |
11.667 |
9.583 |
| 232 |
T |
CMGC/MAPK/ERK/Erk1 |
LVGETPLTPDGPKAN |
28.556 |
10.326 |
| 332 |
T |
CMGC/MAPK/JNK/JNK2 |
GHAIQCNTPGLKPDT |
26.941 |
6.118 |
* Only the results whose Scores are more than 10 are listed here.
- Click here
to download the complete GPS results for this protein entry.
- You can also go to the DOWNLOAD page to get the GPS results for all protein entries.
Pfam Domains (Experimental/Computational Results)
| id |
type |
start |
end |
| Sorry. There is no result for this protein entry. |
Mutation (Experimental Results)
| POSITION |
WILD-TYPE AA |
MUTANT |
DISEASE/NOTES |
REFERENCE |
| Sorry. There is no result for this protein entry. |
Pathway (Experimental Results)
| Pathway Accession Number |
Description |
| Sorry. There is no result for this protein entry. |
Multiple Sequence Alignments (Computational Results)
- Sorry. There is no multiple sequence alignment information for this entry.
Protein Alignment (Computational Results)
- Sorry. There is no ortholog information for this entry.
- Sorry. There is no alignment file for this entry.
