Comprehensive Information

Detailed Information (Experimental Results)

Top

Database ID30
UniProt ID A2A0X2 
Name Type III secreted effector protein
Type Type III secretion system effector (T3SE)
Gene Name tccP2
Organism Escherichia coli O157:H7
Gene Ontology Terms -
Function -
Sequence MINSINSFFSGLPRSISSAIRSSTFTVSQHKSTPNTVKTSSPFSPSNSPASATTIFKVKNSYTESGLQRPTSYTQSSIEKNALHRPLPDVAQRLVQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
Length 297  amino acids
Reference 26120140
IBS
There is no IBS picture for this protein entry.
Sequence Alignment:

Protein Structure (Experimental Results)

Top

PDB Accession Method Resolution Chain Structure Review
Sorry. There is no result for this protein entry.

Disorder Prediction (Computational Results)

Top

Start End Sequence
86 297 PLPDVAQRLVQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
1 83 MINSINSFFSGLPRSISSAIRSSTFTVSQHKSTPNTVKTSSPFSPSNSPASATTIFKVKNSYTESGLQRPTSYTQSSIEKNAL

Disorder Picture (Computational Results)

Top

Kinase-specific Phosphorylation Sites (Computational Results)

Top

Position Code Kinase Peptide Score Cutoff
48 S CMGC/CDK/CDK2/CDK2 SPFSPSNSPASATTI 14.933 6.826
4 S Other/PLK ****MINSINSFFSG 20.565 8.093
10 S CK1/VRK/VRK2 NSINSFFSGLPRSIS 12.25 4
170 T CMGC/CDK/CDC2/CDK1 APNWPAPTPPVQNEQ 11.331 4.168
4 S CK1/VRK/VRK2 ****MINSINSFFSG 23.75 4
217 T CAMK/MAPKAPK/MK5 APNWPAPTPPVQNEQ 12.455 6.633
294 S Other/PEK AEHGINTSKRS**** 32.091 2.678
294 S AGC/GRK/BARK/BARK1 AEHGINTSKRS**** 24.5 3.384
71 T CK1/CK1/CK1-D/CSNK1D ESGLQRPTSYTQSSI 12.5 8.142
217 T CMGC/CDK/CDC2/CDK1 APNWPAPTPPVQNEQ 11.331 4.168
217 T CMGC/MAPK/JNK/JNK2 APNWPAPTPPVQNEQ 36.647 6.118
170 T CMGC/CDK/CDK2/CDC28 APNWPAPTPPVQNEQ 14.056 9.411
33 T CMGC/MAPK/ERK/Erk1 TVSQHKSTPNTVKTS 20.708 10.326
294 S AGC/GRK/BARK AEHGINTSKRS**** 15.512 3.806
7 S Other/PLK *MINSINSFFSGLPR 15.766 8.093
170 T CMGC/MAPK/ERK/Erk1 APNWPAPTPPVQNEQ 13.646 10.326
294 S Other/IKK AEHGINTSKRS**** 11.835 4.573
41 S CMGC/CDK/CDK2/CDK2 PNTVKTSSPFSPSNS 11.43 6.826
48 S CMGC/MAPK/ERK/Erk1 SPFSPSNSPASATTI 18.472 10.326
40 S Atypical/PIKK/FRAP TPNTVKTSSPFSPSN 11.556 8.145
44 S STE/STE20/PAKA/CLA4 VKTSSPFSPSNSPAS 15.5 3.825
44 S CMGC/MAPK VKTSSPFSPSNSPAS 16.578 4.55
17 S CAMK/MAPKAPK/MK5/MAPKAPK5 SGLPRSISSAIRSST 19.545 6.633
41 S CMGC/CDK/CDK5/PHO85 PNTVKTSSPFSPSNS 15.611 7.061
297 S AGC/PKC/PKCa GINTSKRS******* 15.904 3.383
41 S CMGC/MAPK/ERK/Erk1 PNTVKTSSPFSPSNS 23.41 10.326
294 S AGC/PKC/PKCa/PRKCB AEHGINTSKRS**** 19.224 8.434
17 S CAMK/MAPKAPK/MK5 SGLPRSISSAIRSST 19.545 6.633
294 S AGC/GRK AEHGINTSKRS**** 16.621 6.103
170 T CAMK/MAPKAPK/MK5/MAPKAPK5 APNWPAPTPPVQNEQ 12.455 6.633
24 T AGC/PDK1/PKH2 SSAIRSSTFTVSQHK 12.667 5.683
72 S CAMK/MAPKAPK/MK5/MAPKAPK5 SGLQRPTSYTQSSIE 12.091 6.633
297 S AGC/GRK/GRK/GRK GINTSKRS******* 12.611 6.878
72 S AGC/RSK/RSKp90/RPS6KA3 SGLQRPTSYTQSSIE 12.529 8.112
72 S CAMK/CAMKL/CHK1 SGLQRPTSYTQSSIE 13.552 8.03
44 S CMGC/CDK/CDK2/CDK2 VKTSSPFSPSNSPAS 19.383 6.826
53 T STE/STE20/PAKA/PAK3 SNSPASATTIFKVKN 13.533 5.9
33 T CMGC/CDK/CDC2/CDK1 TVSQHKSTPNTVKTS 14.155 4.168
4 S CK1 ****MINSINSFFSG 11.785 5.313
44 S CMGC/MAPK/ERK/Erk2 VKTSSPFSPSNSPAS 28.186 4.61
170 T CAMK/MAPKAPK/MK5 APNWPAPTPPVQNEQ 12.455 6.633
4 S Other/NEK/NEK11 ****MINSINSFFSG 13.667 8.933
48 S CMGC/MAPK/ERK/FUS3 SPFSPSNSPASATTI 11 3.833
44 S CMGC/MAPK/ERK/Erk1 VKTSSPFSPSNSPAS 22.132 10.326
51 S STE/STE20/MST/MST1 SPSNSPASATTIFKV 18.839 2.612
7 S TKL/MLK *MINSINSFFSGLPR 14.08 7.138
48 S CMGC/CDK/CDK2/CDC28 SPFSPSNSPASATTI 14.083 9.411
7 S STE/STE20/YSK *MINSINSFFSGLPR 13 6.05
297 S Atypical/PDHK/PDHK GINTSKRS******* 11.675 2.805
44 S Atypical/PIKK/FRAP VKTSSPFSPSNSPAS 16.917 8.145
48 S CMGC/MAPK/ERK/Erk2 SPFSPSNSPASATTI 16.606 4.61
33 T CMGC/MAPK/ERK/Erk5 TVSQHKSTPNTVKTS 11 4.757
297 S AGC/GRK GINTSKRS******* 14.216 6.103
26 T Other/TTK/TTK AIRSSTFTVSQHKST 53.636 47.968
217 T CMGC/CDK/CDK5/CDK5 APNWPAPTPPVQNEQ 16.235 7.867
297 S AGC/PKC/PKCa/PRKCA GINTSKRS******* 35.682 5.842
72 S Atypical/PIKK/FRAP SGLQRPTSYTQSSIE 16.944 8.145
17 S CAMK/CAMKL SGLPRSISSAIRSST 16.276 6.355
48 S CMGC/CDK/CDK5 SPFSPSNSPASATTI 23.97 6.616
22 S AGC/GRK/GRK/GRK SISSAIRSSTFTVSQ 12.889 6.878
33 T CMGC/MAPK/JNK/JNK2 TVSQHKSTPNTVKTS 29.676 6.118
217 T CMGC/MAPK/ERK/Erk2 APNWPAPTPPVQNEQ 18.522 4.61
48 S CMGC/MAPK/JNK/JNK2 SPFSPSNSPASATTI 41.618 6.118
32 S CAMK/RAD53/CHK2 FTVSQHKSTPNTVKT 15.773 4.788
41 S CMGC/MAPK/p38 PNTVKTSSPFSPSNS 11.074 4.309
41 S CMGC/MAPK/JNK/JNK2 PNTVKTSSPFSPSNS 28.088 6.118
44 S CMGC/CDK/CDK2/CDC28 VKTSSPFSPSNSPAS 13.917 9.411
51 S Other/NEK/NEK11 SPSNSPASATTIFKV 12.667 8.933
51 S CAMK/RAD53/DUN1 SPSNSPASATTIFKV 11 6.017
7 S CK1/VRK/VRK2 *MINSINSFFSGLPR 17.5 4
41 S CMGC/CDK/CDK2/CDC28 PNTVKTSSPFSPSNS 18.222 9.411
293 T AGC/GRK LAEHGINTSKRS*** 13.853 6.103
74 T AGC/RSK/RSKp70 LQRPTSYTQSSIEKN 11.237 3.694
44 S CMGC/CDK/CDC2/CDK1 VKTSSPFSPSNSPAS 17.142 4.168
17 S AGC/RSK/MSK/RPS6KA5 SGLPRSISSAIRSST 12.852 8.69
63 T CAMK/CAMKL FKVKNSYTESGLQRP 12.281 6.355
17 S CAMK/CAMKL/CHK1 SGLPRSISSAIRSST 11.172 8.03
48 S CMGC/CDK/CDK5/CDK5 SPFSPSNSPASATTI 17.531 7.867
41 S CMGC/MAPK PNTVKTSSPFSPSNS 11.805 4.55
15 S CK1/VRK/VRK2 FFSGLPRSISSAIRS 11.75 4
264 T CMGC/MAPK/ERK/Erk2 APNWPAPTPPVQNEQ 18.522 4.61
264 T CMGC/MAPK/ERK/Erk1 APNWPAPTPPVQNEQ 13.646 10.326
10 S Other/NEK/NEK11 NSINSFFSGLPRSIS 13.333 8.933
217 T CMGC/CDK/CDK2/CDC28 APNWPAPTPPVQNEQ 14.056 9.411
33 T CMGC/CDK/CDK5/PHO85 TVSQHKSTPNTVKTS 11.611 7.061
170 T CMGC/MAPK/ERK/Erk2 APNWPAPTPPVQNEQ 18.522 4.61
51 S Other/CDC7 SPSNSPASATTIFKV 15.333 9.583
24 T CAMK/RAD53/CHK2 SSAIRSSTFTVSQHK 14 4.788
51 S Other/CDC7/CDC7 SPSNSPASATTIFKV 15.333 9.583
264 T CAMK/MAPKAPK/MK5 APNWPAPTPPVQNEQ 12.455 6.633
44 S CMGC/CDK/CDK5/CDK5 VKTSSPFSPSNSPAS 17.519 7.867
26 T STE/STE20/MST/MST1 AIRSSTFTVSQHKST 30 2.612
264 T STE/STE20/MST/MST1 APNWPAPTPPVQNEQ 28.29 2.612
170 T STE/STE20/MST/MST1 APNWPAPTPPVQNEQ 28.29 2.612
297 S AGC/PKC/PKCi GINTSKRS******* 11.75 7.442
28 S Atypical/PIKK/ATR RSSTFTVSQHKSTPN 11.362 8.681
272 S STE/STE20/MST PPVQNEQSRPLPDVA 18.421 3.532
40 S CAMK/CAMKL/AMPK/AMPKA2 TPNTVKTSSPFSPSN 11 4.95
41 S CMGC/MAPK/ERK/Erk5 PNTVKTSSPFSPSNS 11.647 4.757
297 S AGC/GRK/BARK GINTSKRS******* 14.186 3.806
44 S CMGC/MAPK/JNK/JNK2 VKTSSPFSPSNSPAS 36.735 6.118
170 T CMGC/CDK/CDK5/CDK5 APNWPAPTPPVQNEQ 16.235 7.867
264 T CMGC/CDK/CDK5/CDK5 APNWPAPTPPVQNEQ 16.235 7.867
48 S Atypical/PIKK/FRAP SPFSPSNSPASATTI 15.722 8.145
24 T STE/STE20/TAO/TAOK1 SSAIRSSTFTVSQHK 11 6.1
293 T AGC/GRK/BARK/BARK1 LAEHGINTSKRS*** 19.786 3.384
41 S CMGC/MAPK/ERK/Erk2 PNTVKTSSPFSPSNS 11.735 4.61
17 S AGC/RSK/RSKp70/RPS6KB2 SGLPRSISSAIRSST 12 5.033
293 T AGC/PKC/PKCa/PRKCA LAEHGINTSKRS*** 25.54 5.842
264 T CMGC/CDK/CDK2/CDC28 APNWPAPTPPVQNEQ 14.056 9.411
170 T Atypical/PIKK/FRAP APNWPAPTPPVQNEQ 14.778 8.145
24 T CAMK/CAMKL SSAIRSSTFTVSQHK 17.171 6.355
41 S CMGC/MAPK/ERK/FUS3 PNTVKTSSPFSPSNS 11.333 3.833
17 S AGC/PKC/PKCi SGLPRSISSAIRSST 11.167 7.442
48 S Other/PLK SPFSPSNSPASATTI 12.961 8.093
294 S Other/PLK AEHGINTSKRS**** 11.727 8.093
33 T CMGC/MAPK/ERK/Erk2 TVSQHKSTPNTVKTS 11.668 4.61
33 T CMGC/CDK/CDK5/CDK5 TVSQHKSTPNTVKTS 12.568 7.867
72 S CAMK/MAPKAPK/MK5 SGLQRPTSYTQSSIE 12.091 6.633
39 T TKL/MLK STPNTVKTSSPFSPS 19.68 7.138
15 S AGC/PKC/PKCa/PRKCB FFSGLPRSISSAIRS 11.069 8.434
264 T Atypical/PIKK/FRAP APNWPAPTPPVQNEQ 14.778 8.145
264 T CAMK/MAPKAPK/MK5/MAPKAPK5 APNWPAPTPPVQNEQ 12.455 6.633
23 S CAMK/MAPKAPK/MNK/MNK1 ISSAIRSSTFTVSQH 11 8.333
32 S CMGC/CDK/CDK4/CDK6 FTVSQHKSTPNTVKT 13.167 3.967
41 S CMGC/CDK/CDK5/CDK5 PNTVKTSSPFSPSNS 17.333 7.867
217 T CMGC/MAPK/ERK/Erk1 APNWPAPTPPVQNEQ 13.646 10.326
24 T AGC/PKC/PKCi SSAIRSSTFTVSQHK 13.604 7.442
41 S CMGC/CDK/CDC2/CDK1 PNTVKTSSPFSPSNS 12.895 4.168
217 T CAMK/MAPKAPK/MK5/MAPKAPK5 APNWPAPTPPVQNEQ 12.455 6.633
217 T Atypical/PIKK/FRAP APNWPAPTPPVQNEQ 14.778 8.145
63 T CAMK/MAPKAPK FKVKNSYTESGLQRP 11.753 6.36
36 T Other/TTK/TTK QHKSTPNTVKTSSPF 61.182 47.968
48 S CAMK/MAPKAPK/MNK/MNK2 SPFSPSNSPASATTI 11 6.869
264 T CMGC/CDK/CDC2/CDK1 APNWPAPTPPVQNEQ 11.331 4.168
33 T CMGC/CDK/CDK2/CDK2 TVSQHKSTPNTVKTS 13.55 6.826
297 S Other/PEK GINTSKRS******* 41.227 2.678
24 T STE/STE20/TAO SSAIRSSTFTVSQHK 11 6.1
24 T STE/STE20/YSK SSAIRSSTFTVSQHK 12 6.05
33 T CMGC/CDK/CDK2/CDC28 TVSQHKSTPNTVKTS 13.639 9.411
71 T STE/STE20/PAKA/PAK1 ESGLQRPTSYTQSSI 13.342 6.979
297 S AGC/PKC/PKCa/PRKCB GINTSKRS******* 28.345 8.434
40 S STE/STE20/MST TPNTVKTSSPFSPSN 33.158 3.532
217 T STE/STE20/MST/MST1 APNWPAPTPPVQNEQ 28.29 2.612
71 T STE/STE20/PAKA ESGLQRPTSYTQSSI 12.093 6.397
72 S CMGC/DYRK/DYRK2 SGLQRPTSYTQSSIE 12.556 7.053
44 S CMGC/MAPK/ERK/Erk5 VKTSSPFSPSNSPAS 17.824 4.757
17 S CAMK/MAPKAPK SGLPRSISSAIRSST 16.636 6.36
293 T AGC/GRK/BARK LAEHGINTSKRS*** 11.023 3.806
297 S AGC/GRK/BARK/BARK1 GINTSKRS******* 24.429 3.384
294 S AGC/PKC/PKCa/PRKCA AEHGINTSKRS**** 23.818 5.842
32 S Other/IKK/IKKb/IKBKB FTVSQHKSTPNTVKT 11.71 6.297
48 S CMGC/CDK/CDK4/CDK6 SPFSPSNSPASATTI 12.333 3.967
41 S Atypical/PIKK/FRAP PNTVKTSSPFSPSNS 16.222 8.145
44 S CMGC/CDK/CDK5 VKTSSPFSPSNSPAS 25.444 6.616
44 S CMGC/MAPK/p38 VKTSSPFSPSNSPAS 13.311 4.309
170 T CMGC/MAPK/JNK/JNK2 APNWPAPTPPVQNEQ 36.647 6.118
264 T CMGC/MAPK/JNK/JNK2 APNWPAPTPPVQNEQ 36.647 6.118
44 S CMGC/CDK/CDC2 VKTSSPFSPSNSPAS 11.811 4.698
48 S CMGC/CDK/CDK5/PHO85 SPFSPSNSPASATTI 12 7.061

* Only the results whose Scores are more than 10 are listed here.

  • Click here to download the complete GPS results for this protein entry.
  • You can also go to the DOWNLOAD page to get the GPS results for all protein entries.

Pfam Domains (Experimental/Computational Results)

Top

id type start end
EspF Pfam 150 196
EspF Pfam 244 290
EspF Pfam 197 243
EspF Pfam 103 149
EspF Pfam 76 102

Mutation (Experimental Results)

Top

POSITION WILD-TYPE AA MUTANT DISEASE/NOTES REFERENCE
Sorry. There is no result for this protein entry.

Pathway (Experimental Results)

Top

Pathway Accession Number Description
Sorry. There is no result for this protein entry.

Multiple Sequence Alignments (Computational Results)

Top

Protein Alignment (Computational Results)

Top