Comprehensive Information

Detailed Information (Experimental Results)

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Database ID33
UniProt ID A2A0X8 
Name Type III secreted effector protein
Type Type III secretion system effector (T3SE)
Gene Name tccP2
Organism Escherichia coli O26:H11
Gene Ontology Terms -
Function -
Sequence MINSINSFFSSLPRSISSAIRSSTFTVSQHKSTPNTVKTSSPFSPSNSPASATTIFKVKNSYTESGLQRPTSYTQSSIEKNALHRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEYIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
Length 250  amino acids
Reference 26120140
IBS
There is no IBS picture for this protein entry.
Sequence Alignment:

Protein Structure (Experimental Results)

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PDB Accession Method Resolution Chain Structure Review
Sorry. There is no result for this protein entry.

Disorder Prediction (Computational Results)

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Start End Sequence
1 83 MINSINSFFSSLPRSISSAIRSSTFTVSQHKSTPNTVKTSSPFSPSNSPASATTIFKVKNSYTESGLQRPTSYTQSSIEKNAL
87 250 LPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEYIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS

Disorder Picture (Computational Results)

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Kinase-specific Phosphorylation Sites (Computational Results)

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Position Code Kinase Peptide Score Cutoff
32 S CMGC/CDK/CDK4/CDK6 FTVSQHKSTPNTVKT 13.167 3.967
17 S CK1/CK1/CK1-D/CSNK1D SSLPRSISSAIRSST 11.15 8.142
48 S CMGC/CDK/CDK5 SPFSPSNSPASATTI 23.97 6.616
44 S CMGC/MAPK/p38 VKTSSPFSPSNSPAS 13.311 4.309
17 S CAMK/CAMKL SSLPRSISSAIRSST 18.668 6.355
217 T CMGC/MAPK/ERK/Erk1 APNWPAPTPPVQNEQ 13.646 10.326
74 T AGC/RSK/RSKp70 LQRPTSYTQSSIEKN 11.237 3.694
51 S Other/CDC7 SPSNSPASATTIFKV 15.333 9.583
40 S CAMK/CAMKL/AMPK/AMPKA2 TPNTVKTSSPFSPSN 11 4.95
32 S Other/IKK/IKKb/IKBKB FTVSQHKSTPNTVKT 11.71 6.297
7 S TKL/MLK *MINSINSFFSSLPR 16.76 7.138
41 S CMGC/MAPK/p38 PNTVKTSSPFSPSNS 11.074 4.309
41 S CMGC/CDK/CDK5/PHO85 PNTVKTSSPFSPSNS 15.611 7.061
4 S Other/PLK ****MINSINSFFSS 22.903 8.093
26 T STE/STE20/MST/MST1 AIRSSTFTVSQHKST 30 2.612
10 S CK1/VRK/VRK2 NSINSFFSSLPRSIS 14.75 4
53 T STE/STE20/PAKA/PAK3 SNSPASATTIFKVKN 13.533 5.9
250 S AGC/PKC/PKCa/PRKCB GINTSKRS******* 28.345 8.434
206 Y TK/EGFR PARNMAEYIPPAPNW 12.687 6.45
250 S AGC/GRK/BARK/BARK1 GINTSKRS******* 24.429 3.384
217 T CAMK/MAPKAPK/MK5/MAPKAPK5 APNWPAPTPPVQNEQ 12.455 6.633
48 S CMGC/MAPK/JNK/JNK2 SPFSPSNSPASATTI 41.618 6.118
246 T AGC/GRK/BARK LAEHGINTSKRS*** 11.023 3.806
41 S CMGC/MAPK/ERK/Erk5 PNTVKTSSPFSPSNS 11.647 4.757
217 T STE/STE20/MST/MST1 APNWPAPTPPVQNEQ 30.065 2.612
44 S CMGC/CDK/CDC2/CDK1 VKTSSPFSPSNSPAS 17.142 4.168
48 S CAMK/MAPKAPK/MNK/MNK2 SPFSPSNSPASATTI 11 6.869
17 S AGC/RSK/MSK/RPS6KA5 SSLPRSISSAIRSST 12.852 8.69
41 S CMGC/MAPK/JNK/JNK2 PNTVKTSSPFSPSNS 28.088 6.118
24 T STE/STE20/TAO SSAIRSSTFTVSQHK 11 6.1
24 T AGC/PKC/PKCi SSAIRSSTFTVSQHK 13.604 7.442
41 S Atypical/PIKK/FRAP PNTVKTSSPFSPSNS 16.222 8.145
41 S CMGC/MAPK/ERK/Erk2 PNTVKTSSPFSPSNS 11.735 4.61
48 S CMGC/MAPK/ERK/FUS3 SPFSPSNSPASATTI 11 3.833
48 S CMGC/CDK/CDK5/CDK5 SPFSPSNSPASATTI 17.531 7.867
250 S Other/PEK GINTSKRS******* 41.227 2.678
40 S STE/STE20/MST TPNTVKTSSPFSPSN 33.158 3.532
44 S CMGC/CDK/CDK5 VKTSSPFSPSNSPAS 25.444 6.616
17 S AGC/PKC/PKCi SSLPRSISSAIRSST 11.167 7.442
44 S CMGC/MAPK VKTSSPFSPSNSPAS 16.578 4.55
44 S CMGC/MAPK/ERK/Erk5 VKTSSPFSPSNSPAS 17.824 4.757
44 S Atypical/PIKK/FRAP VKTSSPFSPSNSPAS 16.917 8.145
217 T CMGC/CDK/CDK2/CDC28 APNWPAPTPPVQNEQ 14.056 9.411
72 S AGC/RSK/RSKp90/RPS6KA3 SGLQRPTSYTQSSIE 12.529 8.112
41 S CMGC/MAPK/ERK/FUS3 PNTVKTSSPFSPSNS 11.333 3.833
246 T AGC/GRK/BARK/BARK1 LAEHGINTSKRS*** 19.786 3.384
33 T CMGC/CDK/CDK2/CDK2 TVSQHKSTPNTVKTS 13.55 6.826
7 S CK1/VRK/VRK2 *MINSINSFFSSLPR 17.5 4
48 S CMGC/CDK/CDK2/CDK2 SPFSPSNSPASATTI 14.933 6.826
36 T Other/TTK/TTK QHKSTPNTVKTSSPF 61.182 47.968
44 S CMGC/MAPK/ERK/Erk1 VKTSSPFSPSNSPAS 22.132 10.326
250 S AGC/PKC/PKCa GINTSKRS******* 15.904 3.383
24 T CAMK/RAD53/CHK2 SSAIRSSTFTVSQHK 20.114 4.788
41 S CMGC/CDK/CDK5/CDK5 PNTVKTSSPFSPSNS 17.333 7.867
41 S CMGC/CDK/CDK2/CDC28 PNTVKTSSPFSPSNS 18.222 9.411
44 S CMGC/MAPK/JNK/JNK2 VKTSSPFSPSNSPAS 36.735 6.118
17 S CAMK/CAMKL/CHK1 SSLPRSISSAIRSST 11.31 8.03
33 T CMGC/CDK/CDK5/PHO85 TVSQHKSTPNTVKTS 11.611 7.061
247 S AGC/GRK/BARK AEHGINTSKRS**** 15.512 3.806
217 T CAMK/MAPKAPK/MK5 APNWPAPTPPVQNEQ 12.455 6.633
225 S STE/STE20/MST PPVQNEQSRPLPDVA 18.421 3.532
250 S AGC/PKC/PKCi GINTSKRS******* 11.75 7.442
40 S Atypical/PIKK/FRAP TPNTVKTSSPFSPSN 11.556 8.145
48 S CMGC/CDK/CDK2/CDC28 SPFSPSNSPASATTI 14.083 9.411
24 T STE/STE20/TAO/TAOK1 SSAIRSSTFTVSQHK 11 6.1
247 S AGC/GRK/BARK/BARK1 AEHGINTSKRS**** 24.5 3.384
33 T CMGC/MAPK/ERK/Erk1 TVSQHKSTPNTVKTS 20.708 10.326
247 S Other/PLK AEHGINTSKRS**** 11.727 8.093
28 S Atypical/PIKK/ATR RSSTFTVSQHKSTPN 11.362 8.681
41 S CMGC/MAPK/ERK/Erk1 PNTVKTSSPFSPSNS 23.41 10.326
33 T CMGC/CDK/CDC2/CDK1 TVSQHKSTPNTVKTS 14.155 4.168
10 S AGC/NDR/NDR/NDR1 NSINSFFSSLPRSIS 11 6
4 S CK1 ****MINSINSFFSS 13.014 5.313
24 T AGC/PDK1/PKH2 SSAIRSSTFTVSQHK 12.667 5.683
44 S CMGC/MAPK/ERK/Erk2 VKTSSPFSPSNSPAS 28.186 4.61
33 T CMGC/MAPK/ERK/Erk2 TVSQHKSTPNTVKTS 11.668 4.61
48 S CMGC/MAPK/ERK/Erk1 SPFSPSNSPASATTI 18.472 10.326
217 T CMGC/CDK/CDC2/CDK1 APNWPAPTPPVQNEQ 11.331 4.168
217 T Atypical/PIKK/FRAP APNWPAPTPPVQNEQ 14.778 8.145
51 S CAMK/RAD53/DUN1 SPSNSPASATTIFKV 11 6.017
246 T AGC/GRK LAEHGINTSKRS*** 13.853 6.103
17 S CAMK/MAPKAPK/MK5/MAPKAPK5 SSLPRSISSAIRSST 19.909 6.633
44 S CMGC/CDK/CDK5/CDK5 VKTSSPFSPSNSPAS 17.519 7.867
250 S Atypical/PDHK/PDHK GINTSKRS******* 11.675 2.805
250 S AGC/GRK/BARK GINTSKRS******* 14.186 3.806
48 S CMGC/CDK/CDK4/CDK6 SPFSPSNSPASATTI 12.333 3.967
51 S STE/STE20/MST/MST1 SPSNSPASATTIFKV 18.839 2.612
44 S CMGC/CDK/CDK2/CDK2 VKTSSPFSPSNSPAS 19.383 6.826
71 T STE/STE20/PAKA ESGLQRPTSYTQSSI 12.093 6.397
247 S Other/PEK AEHGINTSKRS**** 32.091 2.678
51 S Other/NEK/NEK11 SPSNSPASATTIFKV 12.667 8.933
41 S CMGC/CDK/CDK2/CDK2 PNTVKTSSPFSPSNS 11.43 6.826
22 S AGC/GRK/GRK/GRK SISSAIRSSTFTVSQ 12.889 6.878
23 S CAMK/MAPKAPK/MNK/MNK1 ISSAIRSSTFTVSQH 11 8.333
39 T TKL/MLK STPNTVKTSSPFSPS 19.68 7.138
32 S CAMK/RAD53/CHK2 FTVSQHKSTPNTVKT 15.773 4.788
33 T CMGC/CDK/CDK2/CDC28 TVSQHKSTPNTVKTS 13.639 9.411
11 S CK1/VRK/VRK2 SINSFFSSLPRSISS 15 4
63 T CAMK/CAMKL FKVKNSYTESGLQRP 12.281 6.355
48 S Other/PLK SPFSPSNSPASATTI 12.961 8.093
44 S CMGC/CDK/CDC2 VKTSSPFSPSNSPAS 11.811 4.698
15 S AGC/PKC/PKCa/PRKCB FFSSLPRSISSAIRS 11.069 8.434
247 S AGC/PKC/PKCa/PRKCA AEHGINTSKRS**** 23.818 5.842
250 S AGC/GRK GINTSKRS******* 14.216 6.103
217 T CMGC/MAPK/ERK/Erk2 APNWPAPTPPVQNEQ 18.522 4.61
33 T CMGC/MAPK/ERK/Erk5 TVSQHKSTPNTVKTS 11 4.757
246 T AGC/PKC/PKCa/PRKCA LAEHGINTSKRS*** 25.54 5.842
247 S AGC/GRK AEHGINTSKRS**** 16.621 6.103
71 T CK1/CK1/CK1-D/CSNK1D ESGLQRPTSYTQSSI 12.5 8.142
24 T CAMK/CAMKL SSAIRSSTFTVSQHK 17.281 6.355
72 S Atypical/PIKK/FRAP SGLQRPTSYTQSSIE 16.944 8.145
72 S CMGC/DYRK/DYRK2 SGLQRPTSYTQSSIE 12.556 7.053
48 S CMGC/CDK/CDK5/PHO85 SPFSPSNSPASATTI 12 7.061
44 S STE/STE20/PAKA/CLA4 VKTSSPFSPSNSPAS 15.5 3.825
63 T CAMK/MAPKAPK FKVKNSYTESGLQRP 11.753 6.36
10 S Other/NEK/NEK11 NSINSFFSSLPRSIS 11.667 8.933
17 S CAMK/MAPKAPK/MK5 SSLPRSISSAIRSST 19.909 6.633
15 S CK1/VRK/VRK2 FFSSLPRSISSAIRS 11.75 4
4 S CK1/VRK/VRK2 ****MINSINSFFSS 23.75 4
51 S Other/CDC7/CDC7 SPSNSPASATTIFKV 15.333 9.583
250 S AGC/PKC/PKCa/PRKCA GINTSKRS******* 35.682 5.842
72 S CAMK/CAMKL/CHK1 SGLQRPTSYTQSSIE 13.552 8.03
247 S AGC/PKC/PKCa/PRKCB AEHGINTSKRS**** 19.224 8.434
41 S CMGC/MAPK PNTVKTSSPFSPSNS 11.805 4.55
217 T CMGC/MAPK/JNK/JNK2 APNWPAPTPPVQNEQ 36.647 6.118
48 S Atypical/PIKK/FRAP SPFSPSNSPASATTI 15.722 8.145
33 T CMGC/MAPK/JNK/JNK2 TVSQHKSTPNTVKTS 29.676 6.118
7 S Other/PLK *MINSINSFFSSLPR 16.247 8.093
17 S CAMK/MAPKAPK SSLPRSISSAIRSST 17.065 6.36
26 T Other/TTK/TTK AIRSSTFTVSQHKST 53.636 47.968
72 S CAMK/MAPKAPK/MK5 SGLQRPTSYTQSSIE 12.091 6.633
44 S CMGC/CDK/CDK2/CDC28 VKTSSPFSPSNSPAS 13.917 9.411
72 S CAMK/MAPKAPK/MK5/MAPKAPK5 SGLQRPTSYTQSSIE 12.091 6.633
71 T STE/STE20/PAKA/PAK1 ESGLQRPTSYTQSSI 13.342 6.979
4 S Other/NEK/NEK11 ****MINSINSFFSS 13.667 8.933
247 S Other/IKK AEHGINTSKRS**** 11.835 4.573
17 S AGC/RSK/RSKp70/RPS6KB2 SSLPRSISSAIRSST 12 5.033
217 T CMGC/CDK/CDK5/CDK5 APNWPAPTPPVQNEQ 16.235 7.867
250 S AGC/GRK/GRK/GRK GINTSKRS******* 12.611 6.878
41 S CMGC/CDK/CDC2/CDK1 PNTVKTSSPFSPSNS 12.895 4.168
33 T CMGC/CDK/CDK5/CDK5 TVSQHKSTPNTVKTS 12.568 7.867
7 S STE/STE20/YSK *MINSINSFFSSLPR 13 6.05
24 T STE/STE20/YSK SSAIRSSTFTVSQHK 12 6.05
48 S CMGC/MAPK/ERK/Erk2 SPFSPSNSPASATTI 16.606 4.61

* Only the results whose Scores are more than 10 are listed here.

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Pfam Domains (Experimental/Computational Results)

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id type start end
EspF Pfam 76 102
EspF Pfam 150 196
EspF Pfam 197 243
EspF Pfam 103 149

Mutation (Experimental Results)

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POSITION WILD-TYPE AA MUTANT DISEASE/NOTES REFERENCE
Sorry. There is no result for this protein entry.

Pathway (Experimental Results)

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Pathway Accession Number Description
Sorry. There is no result for this protein entry.

Multiple Sequence Alignments (Computational Results)

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Protein Alignment (Computational Results)

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