Comprehensive Information

Detailed Information (Experimental Results)

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Database ID36
UniProt ID A2A0Z2 
Name Type III secreted effector protein
Type Type III secretion system effector (T3SE)
Gene Name tccP2
Organism Escherichia coli O103:H2
Gene Ontology Terms -
Function -
Sequence MINSINSFFSSLPRSISSAIRSSTFTVSQHKSTPNTVKTSSPFSPSNSPASATTIFKVKNSYTESGLQRPTSYTQSSIEKNALHRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEYIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
Length 250  amino acids
Reference 26120140
IBS
There is no IBS picture for this protein entry.
Sequence Alignment:

Protein Structure (Experimental Results)

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PDB Accession Method Resolution Chain Structure Review
Sorry. There is no result for this protein entry.

Disorder Prediction (Computational Results)

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Start End Sequence
1 83 MINSINSFFSSLPRSISSAIRSSTFTVSQHKSTPNTVKTSSPFSPSNSPASATTIFKVKNSYTESGLQRPTSYTQSSIEKNAL
87 250 LPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEYIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS

Disorder Picture (Computational Results)

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Kinase-specific Phosphorylation Sites (Computational Results)

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Position Code Kinase Peptide Score Cutoff
44 S Atypical/PIKK/FRAP VKTSSPFSPSNSPAS 16.917 8.145
206 Y TK/EGFR PARNMAEYIPPAPNW 12.687 6.45
17 S CK1/CK1/CK1-D/CSNK1D SSLPRSISSAIRSST 11.15 8.142
17 S AGC/RSK/RSKp70/RPS6KB2 SSLPRSISSAIRSST 12 5.033
4 S CK1/VRK/VRK2 ****MINSINSFFSS 23.75 4
250 S Other/PEK GINTSKRS******* 41.227 2.678
33 T CMGC/CDK/CDK5/CDK5 TVSQHKSTPNTVKTS 12.568 7.867
72 S CAMK/CAMKL/CHK1 SGLQRPTSYTQSSIE 13.552 8.03
41 S CMGC/MAPK/ERK/Erk2 PNTVKTSSPFSPSNS 11.735 4.61
40 S Atypical/PIKK/FRAP TPNTVKTSSPFSPSN 11.556 8.145
7 S TKL/MLK *MINSINSFFSSLPR 16.76 7.138
44 S CMGC/CDK/CDK5/CDK5 VKTSSPFSPSNSPAS 17.519 7.867
33 T CMGC/CDK/CDK5/PHO85 TVSQHKSTPNTVKTS 11.611 7.061
247 S Other/PLK AEHGINTSKRS**** 11.727 8.093
217 T CMGC/CDK/CDC2/CDK1 APNWPAPTPPVQNEQ 11.331 4.168
44 S CMGC/MAPK/ERK/Erk2 VKTSSPFSPSNSPAS 28.186 4.61
246 T AGC/GRK/BARK LAEHGINTSKRS*** 11.023 3.806
7 S Other/PLK *MINSINSFFSSLPR 16.247 8.093
23 S CAMK/MAPKAPK/MNK/MNK1 ISSAIRSSTFTVSQH 11 8.333
17 S AGC/RSK/MSK/RPS6KA5 SSLPRSISSAIRSST 12.852 8.69
33 T CMGC/MAPK/ERK/Erk1 TVSQHKSTPNTVKTS 20.708 10.326
24 T STE/STE20/TAO SSAIRSSTFTVSQHK 11 6.1
41 S CMGC/CDK/CDK5/CDK5 PNTVKTSSPFSPSNS 17.333 7.867
10 S CK1/VRK/VRK2 NSINSFFSSLPRSIS 14.75 4
32 S CAMK/RAD53/CHK2 FTVSQHKSTPNTVKT 15.773 4.788
71 T STE/STE20/PAKA ESGLQRPTSYTQSSI 12.093 6.397
51 S STE/STE20/MST/MST1 SPSNSPASATTIFKV 18.839 2.612
247 S AGC/PKC/PKCa/PRKCA AEHGINTSKRS**** 23.818 5.842
41 S Atypical/PIKK/FRAP PNTVKTSSPFSPSNS 16.222 8.145
72 S CAMK/MAPKAPK/MK5/MAPKAPK5 SGLQRPTSYTQSSIE 12.091 6.633
217 T CMGC/CDK/CDK5/CDK5 APNWPAPTPPVQNEQ 16.235 7.867
33 T CMGC/MAPK/ERK/Erk2 TVSQHKSTPNTVKTS 11.668 4.61
44 S STE/STE20/PAKA/CLA4 VKTSSPFSPSNSPAS 15.5 3.825
250 S AGC/PKC/PKCa/PRKCB GINTSKRS******* 28.345 8.434
51 S Other/NEK/NEK11 SPSNSPASATTIFKV 12.667 8.933
48 S CMGC/MAPK/ERK/Erk2 SPFSPSNSPASATTI 16.606 4.61
41 S CMGC/CDK/CDK2/CDC28 PNTVKTSSPFSPSNS 18.222 9.411
48 S CMGC/CDK/CDK4/CDK6 SPFSPSNSPASATTI 12.333 3.967
250 S AGC/GRK/BARK/BARK1 GINTSKRS******* 24.429 3.384
15 S AGC/PKC/PKCa/PRKCB FFSSLPRSISSAIRS 11.069 8.434
11 S CK1/VRK/VRK2 SINSFFSSLPRSISS 15 4
17 S CAMK/MAPKAPK SSLPRSISSAIRSST 17.065 6.36
40 S STE/STE20/MST TPNTVKTSSPFSPSN 33.158 3.532
48 S CAMK/MAPKAPK/MNK/MNK2 SPFSPSNSPASATTI 11 6.869
250 S AGC/PKC/PKCi GINTSKRS******* 11.75 7.442
250 S AGC/PKC/PKCa GINTSKRS******* 15.904 3.383
41 S CMGC/MAPK/p38 PNTVKTSSPFSPSNS 11.074 4.309
41 S CMGC/MAPK/ERK/FUS3 PNTVKTSSPFSPSNS 11.333 3.833
48 S CMGC/CDK/CDK2/CDK2 SPFSPSNSPASATTI 14.933 6.826
17 S CAMK/CAMKL SSLPRSISSAIRSST 18.668 6.355
48 S CMGC/MAPK/ERK/Erk1 SPFSPSNSPASATTI 18.472 10.326
247 S AGC/GRK/BARK AEHGINTSKRS**** 15.512 3.806
24 T CAMK/RAD53/CHK2 SSAIRSSTFTVSQHK 20.114 4.788
41 S CMGC/MAPK/ERK/Erk5 PNTVKTSSPFSPSNS 11.647 4.757
247 S Other/IKK AEHGINTSKRS**** 11.835 4.573
33 T CMGC/CDK/CDC2/CDK1 TVSQHKSTPNTVKTS 14.155 4.168
44 S CMGC/CDK/CDK2/CDC28 VKTSSPFSPSNSPAS 13.917 9.411
217 T STE/STE20/MST/MST1 APNWPAPTPPVQNEQ 30.065 2.612
17 S CAMK/MAPKAPK/MK5/MAPKAPK5 SSLPRSISSAIRSST 19.909 6.633
4 S CK1 ****MINSINSFFSS 13.014 5.313
48 S CMGC/CDK/CDK2/CDC28 SPFSPSNSPASATTI 14.083 9.411
247 S Other/PEK AEHGINTSKRS**** 32.091 2.678
217 T CAMK/MAPKAPK/MK5 APNWPAPTPPVQNEQ 12.455 6.633
32 S CMGC/CDK/CDK4/CDK6 FTVSQHKSTPNTVKT 13.167 3.967
217 T CMGC/MAPK/ERK/Erk1 APNWPAPTPPVQNEQ 13.646 10.326
225 S STE/STE20/MST PPVQNEQSRPLPDVA 18.421 3.532
33 T CMGC/CDK/CDK2/CDK2 TVSQHKSTPNTVKTS 13.55 6.826
44 S CMGC/MAPK/p38 VKTSSPFSPSNSPAS 13.311 4.309
44 S CMGC/MAPK/JNK/JNK2 VKTSSPFSPSNSPAS 36.735 6.118
217 T CMGC/MAPK/ERK/Erk2 APNWPAPTPPVQNEQ 18.522 4.61
17 S AGC/PKC/PKCi SSLPRSISSAIRSST 11.167 7.442
72 S CMGC/DYRK/DYRK2 SGLQRPTSYTQSSIE 12.556 7.053
51 S CAMK/RAD53/DUN1 SPSNSPASATTIFKV 11 6.017
74 T AGC/RSK/RSKp70 LQRPTSYTQSSIEKN 11.237 3.694
41 S CMGC/CDK/CDC2/CDK1 PNTVKTSSPFSPSNS 12.895 4.168
71 T STE/STE20/PAKA/PAK1 ESGLQRPTSYTQSSI 13.342 6.979
40 S CAMK/CAMKL/AMPK/AMPKA2 TPNTVKTSSPFSPSN 11 4.95
72 S CAMK/MAPKAPK/MK5 SGLQRPTSYTQSSIE 12.091 6.633
48 S CMGC/CDK/CDK5/PHO85 SPFSPSNSPASATTI 12 7.061
4 S Other/NEK/NEK11 ****MINSINSFFSS 13.667 8.933
246 T AGC/PKC/PKCa/PRKCA LAEHGINTSKRS*** 25.54 5.842
33 T CMGC/MAPK/JNK/JNK2 TVSQHKSTPNTVKTS 29.676 6.118
246 T AGC/GRK LAEHGINTSKRS*** 13.853 6.103
246 T AGC/GRK/BARK/BARK1 LAEHGINTSKRS*** 19.786 3.384
7 S CK1/VRK/VRK2 *MINSINSFFSSLPR 17.5 4
53 T STE/STE20/PAKA/PAK3 SNSPASATTIFKVKN 13.533 5.9
10 S AGC/NDR/NDR/NDR1 NSINSFFSSLPRSIS 11 6
44 S CMGC/CDK/CDK2/CDK2 VKTSSPFSPSNSPAS 19.383 6.826
26 T Other/TTK/TTK AIRSSTFTVSQHKST 53.636 47.968
247 S AGC/GRK/BARK/BARK1 AEHGINTSKRS**** 24.5 3.384
17 S CAMK/CAMKL/CHK1 SSLPRSISSAIRSST 11.31 8.03
41 S CMGC/CDK/CDK2/CDK2 PNTVKTSSPFSPSNS 11.43 6.826
217 T Atypical/PIKK/FRAP APNWPAPTPPVQNEQ 14.778 8.145
41 S CMGC/CDK/CDK5/PHO85 PNTVKTSSPFSPSNS 15.611 7.061
48 S CMGC/CDK/CDK5 SPFSPSNSPASATTI 23.97 6.616
4 S Other/PLK ****MINSINSFFSS 22.903 8.093
41 S CMGC/MAPK PNTVKTSSPFSPSNS 11.805 4.55
250 S Atypical/PDHK/PDHK GINTSKRS******* 11.675 2.805
63 T CAMK/CAMKL FKVKNSYTESGLQRP 12.281 6.355
15 S CK1/VRK/VRK2 FFSSLPRSISSAIRS 11.75 4
48 S Atypical/PIKK/FRAP SPFSPSNSPASATTI 15.722 8.145
39 T TKL/MLK STPNTVKTSSPFSPS 19.68 7.138
250 S AGC/GRK/BARK GINTSKRS******* 14.186 3.806
10 S Other/NEK/NEK11 NSINSFFSSLPRSIS 11.667 8.933
250 S AGC/GRK/GRK/GRK GINTSKRS******* 12.611 6.878
48 S CMGC/MAPK/JNK/JNK2 SPFSPSNSPASATTI 41.618 6.118
28 S Atypical/PIKK/ATR RSSTFTVSQHKSTPN 11.362 8.681
48 S CMGC/MAPK/ERK/FUS3 SPFSPSNSPASATTI 11 3.833
63 T CAMK/MAPKAPK FKVKNSYTESGLQRP 11.753 6.36
44 S CMGC/MAPK/ERK/Erk1 VKTSSPFSPSNSPAS 22.132 10.326
44 S CMGC/CDK/CDK5 VKTSSPFSPSNSPAS 25.444 6.616
71 T CK1/CK1/CK1-D/CSNK1D ESGLQRPTSYTQSSI 12.5 8.142
33 T CMGC/CDK/CDK2/CDC28 TVSQHKSTPNTVKTS 13.639 9.411
217 T CMGC/CDK/CDK2/CDC28 APNWPAPTPPVQNEQ 14.056 9.411
7 S STE/STE20/YSK *MINSINSFFSSLPR 13 6.05
247 S AGC/GRK AEHGINTSKRS**** 16.621 6.103
33 T CMGC/MAPK/ERK/Erk5 TVSQHKSTPNTVKTS 11 4.757
24 T STE/STE20/YSK SSAIRSSTFTVSQHK 12 6.05
24 T STE/STE20/TAO/TAOK1 SSAIRSSTFTVSQHK 11 6.1
250 S AGC/GRK GINTSKRS******* 14.216 6.103
72 S AGC/RSK/RSKp90/RPS6KA3 SGLQRPTSYTQSSIE 12.529 8.112
22 S AGC/GRK/GRK/GRK SISSAIRSSTFTVSQ 12.889 6.878
41 S CMGC/MAPK/ERK/Erk1 PNTVKTSSPFSPSNS 23.41 10.326
247 S AGC/PKC/PKCa/PRKCB AEHGINTSKRS**** 19.224 8.434
44 S CMGC/MAPK/ERK/Erk5 VKTSSPFSPSNSPAS 17.824 4.757
17 S CAMK/MAPKAPK/MK5 SSLPRSISSAIRSST 19.909 6.633
24 T AGC/PKC/PKCi SSAIRSSTFTVSQHK 13.604 7.442
26 T STE/STE20/MST/MST1 AIRSSTFTVSQHKST 30 2.612
36 T Other/TTK/TTK QHKSTPNTVKTSSPF 61.182 47.968
48 S Other/PLK SPFSPSNSPASATTI 12.961 8.093
250 S AGC/PKC/PKCa/PRKCA GINTSKRS******* 35.682 5.842
48 S CMGC/CDK/CDK5/CDK5 SPFSPSNSPASATTI 17.531 7.867
217 T CAMK/MAPKAPK/MK5/MAPKAPK5 APNWPAPTPPVQNEQ 12.455 6.633
24 T CAMK/CAMKL SSAIRSSTFTVSQHK 17.281 6.355
44 S CMGC/CDK/CDC2 VKTSSPFSPSNSPAS 11.811 4.698
51 S Other/CDC7/CDC7 SPSNSPASATTIFKV 15.333 9.583
72 S Atypical/PIKK/FRAP SGLQRPTSYTQSSIE 16.944 8.145
32 S Other/IKK/IKKb/IKBKB FTVSQHKSTPNTVKT 11.71 6.297
44 S CMGC/CDK/CDC2/CDK1 VKTSSPFSPSNSPAS 17.142 4.168
44 S CMGC/MAPK VKTSSPFSPSNSPAS 16.578 4.55
41 S CMGC/MAPK/JNK/JNK2 PNTVKTSSPFSPSNS 28.088 6.118
51 S Other/CDC7 SPSNSPASATTIFKV 15.333 9.583
217 T CMGC/MAPK/JNK/JNK2 APNWPAPTPPVQNEQ 36.647 6.118
24 T AGC/PDK1/PKH2 SSAIRSSTFTVSQHK 12.667 5.683

* Only the results whose Scores are more than 10 are listed here.

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Pfam Domains (Experimental/Computational Results)

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id type start end
EspF Pfam 103 149
EspF Pfam 150 196
EspF Pfam 197 243
EspF Pfam 76 102

Mutation (Experimental Results)

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POSITION WILD-TYPE AA MUTANT DISEASE/NOTES REFERENCE
Sorry. There is no result for this protein entry.

Pathway (Experimental Results)

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Pathway Accession Number Description
Sorry. There is no result for this protein entry.

Multiple Sequence Alignments (Computational Results)

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Protein Alignment (Computational Results)

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