Comprehensive Information

Detailed Information (Experimental Results)

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Database ID41
UniProt ID A2I8A2 
Name HsvB type III effector
Type Type III secretion system effector (T3SE)
Gene Name hsvB
Organism Pantoea agglomerans pv. gypsophilae
Gene Ontology Terms -
Function -
Sequence MWHNINPYGAPPFSNRAPDGEPPAADPPPQGTAGGTPPLRDDPRAAPYPEDEVLTEWFSDCATIGGTDHGVIIDYGRALRRFSGFLSQNGLPALSAPGRLDDPDRLRRDAHVYIDRFPQPTNKKYLIPSLNRLIDLVTSGADRITIRGPKRPRRTVPDADEAQIKAAFPGRDGYSVNLTTSARAYSAWLHANGRPGLSDTDWLLSEQADADAAAYSWAHPGYAGRVNIVLAHLRARAGGEVPLIAKNQNTRTIPLADQRLARAYRDVAEDRAGACGIVYKKGKDGRDAIDRSITLLRSFSAWRTARGLPALTDHLHDPTLLTDAQMFVEEKSQAGRALNTTRRTLYMLNAALELLRASFPPGTPVTLPEEPADSFALPGSDWSGWGMSLSLGGHGPADSDSVFGGLAPLDSRERFSSDGLSGTPASGLPETGEVNRPGPDGAPFVSMRDAVPPFRPDGVGFASGEGLSCLLDSILQCYHNIRRGHGAPRGLTDWLDGEVRRVREALSAQGVDLVPARGEIDIYGGPGSYLAGAMGLRLQVIQAEFQEEPDGTYVRYTSHPEMGRSDAPLVRLLHTPGHFQPLWG
Length 584  amino acids
Reference 23437191
IBS
There is no IBS picture for this protein entry.
Sequence Alignment:

Protein Structure (Experimental Results)

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PDB Accession Method Resolution Chain Structure Review
Sorry. There is no result for this protein entry.

Disorder Prediction (Computational Results)

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Start End Sequence
358 458 SFPPGTPVTLPEEPADSFALPGSDWSGWGMSLSLGGHGPADSDSVFGGLAPLDSRERFSSDGLSGTPASGLPETGEVNRPGPDGAPFVSMRDAVPPFRPDG
335 337 GRA
549 550 PD
1 51 MWHNINPYGAPPFSNRAPDGEPPAADPPPQGTAGGTPPLRDDPRAAPYPED
580 584 QPLWG
558 566 SHPEMGRSD
330 332 EKS
92 107 PALSAPGRLDDPDRLR
282 287 GKDGRD
144 163 ITIRGPKRPRRTVPDADEAQ

Disorder Picture (Computational Results)

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Kinase-specific Phosphorylation Sites (Computational Results)

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Position Code Kinase Peptide Score Cutoff
374 S STE/STE20/TAO/TAOK1 LPEEPADSFALPGSD 13 6.1
423 T CMGC/CDK/CDK2/CDK2 SSDGLSGTPASGLPE 18.792 6.826
416 S Other/NEK/NEK11 LDSRERFSSDGLSGT 19.667 8.933
575 T CMGC/CDK/CDK2/CDK2 PLVRLLHTPGHFQPL 16.456 6.826
252 T Other/TTK/TTK AKNQNTRTIPLADQR 53.455 47.968
426 S Atypical/PIKK/FRAP GLSGTPASGLPETGE 11.389 8.145
575 T CMGC/CDK/CDK5/CDK5 PLVRLLHTPGHFQPL 14.198 7.867
492 T STE/STE7/MEK1/MAP2K2 HGAPRGLTDWLDGEV 11 7
300 S CAMK/MAPKAPK ITLLRSFSAWRTARG 15.091 6.36
363 T CMGC/MAPK RASFPPGTPVTLPEE 12.025 4.55
423 T CMGC/CDK/CDK5 SSDGLSGTPASGLPE 12.485 6.616
322 T STE/STE7/MEK1/MAP2K2 LHDPTLLTDAQMFVE 11 7
363 T CMGC/MAPK/ERK/Erk1 RASFPPGTPVTLPEE 21.562 10.326
426 S TKL/LISK/LIMK/LIMK1 GLSGTPASGLPETGE 14 6
557 T STE/STE20/FRAY/STLK3 DGTYVRYTSHPEMGR 14.667 2.983
553 Y TK/PDGFR/PDGFRA QEEPDGTYVRYTSHP 14.1 8.814
175 S AGC/GRK FPGRDGYSVNLTTSA 11.698 6.103
358 S Atypical/PDHK/PDHK ALELLRASFPPGTPV 22.875 2.805
174 Y TK/Trk/TRKA AFPGRDGYSVNLTTS 14.8 11.95
279 Y TK/Fer/FEs AGACGIVYKKGKDGR 12.364 5.958
417 S CAMK/CAMKL/PASK/PASK DSRERFSSDGLSGTP 14.333 5.4
8 Y TK/Eph/EphB1 MWHNINPYGAPPFSN 11.333 7.967
155 T STE/STE20/PAKA GPKRPRRTVPDADEA 12.791 6.397
75 Y TK/Trk/TRKA DHGVIIDYGRALRRF 18 11.95
431 T Atypical/PIKK/FRAP PASGLPETGEVNRPG 11.889 8.145
83 S Other/NEK/NEK11 GRALRRFSGFLSQNG 16.333 8.933
215 Y TK/Csk/CSK ADADAAAYSWAHPGY 16.926 9.741
95 S CAMK/CAMKL/AMPK/AMPKA2 QNGLPALSAPGRLDD 11.25 4.95
366 T Atypical/PIKK/FRAP FPPGTPVTLPEEPAD 11.306 8.145
346 Y TK/Fak/PYK2 NTTRRTLYMLNAALE 11.2 8.11
426 S TKL/LISK/LIMK GLSGTPASGLPETGE 14 6
374 S STE/STE20/TAO LPEEPADSFALPGSD 13 6.1
423 T CMGC/CDK/CDK2/CDC28 SSDGLSGTPASGLPE 17.611 9.411
63 T Other/TTK/TTK EWFSDCATIGGTDHG 54.818 47.968
312 T STE/STE7/MEK1/MAP2K2 ARGLPALTDHLHDPT 11 7
300 S CMGC/CDK/CDK2/CDC28 ITLLRSFSAWRTARG 11.917 9.411
304 T Other/TTK/TTK RSFSAWRTARGLPAL 50.364 47.968
113 Y TK/Axl/MER LRRDAHVYIDRFPQP 12.25 11.588
174 Y TK/Jak/JAK2 AFPGRDGYSVNLTTS 12 9.766
507 S CAMK/MAPKAPK/MK5 RRVREALSAQGVDLV 12.909 6.633
492 T STE/STE20/MST HGAPRGLTDWLDGEV 71.974 3.532
83 S AGC/PKG/PRKG1 GRALRRFSGFLSQNG 11.233 6.847
552 T Other/TTK/TTK FQEEPDGTYVRYTSH 55.182 47.968
363 T CMGC/CDK/CDK2/CDK2 RASFPPGTPVTLPEE 14.725 6.826
423 T CK1/TTBK/TTBK1 SSDGLSGTPASGLPE 11.375 5.133
575 T CMGC/CDK/CDK2/CDC28 PLVRLLHTPGHFQPL 12.944 9.411
294 T CAMK/MAPKAPK DAIDRSITLLRSFSA 15.494 6.36
36 T CK1/TTBK/TTBK1 PQGTAGGTPPLRDDP 11 5.133
181 S Atypical/Alpha/ChaK/TRPM7 YSVNLTTSARAYSAW 11.286 4.914
363 T Atypical/PIKK/FRAP RASFPPGTPVTLPEE 16.472 8.145
36 T CMGC/CDK/CDK5/CDK5 PQGTAGGTPPLRDDP 14.827 7.867
388 S STE/STE20/KHS DWSGWGMSLSLGGHG 11.5 6.762
423 T CMGC/DYRK/DYRK2 SSDGLSGTPASGLPE 11.278 7.053
294 T Other/TTK/TTK DAIDRSITLLRSFSA 51.818 47.968
423 T CMGC/CDK/CDK5/CDK5 SSDGLSGTPASGLPE 17.42 7.867
523 Y TK/Eph/EphB1 ARGEIDIYGGPGSYL 11.667 7.967
558 S AGC/RSK/MSK/RPS6KA5 GTYVRYTSHPEMGRS 13 8.69
423 T CMGC/MAPK/p38 SSDGLSGTPASGLPE 11.326 4.309
528 S Atypical/PIKK/FRAP DIYGGPGSYLAGAMG 12.194 8.145
523 Y TK/Fak/PYK2 ARGEIDIYGGPGSYL 12.3 8.11
83 S STE/STE20/PAKA/PAK1 GRALRRFSGFLSQNG 11.263 6.979
83 S CAMK/CAMKL/CHK1 GRALRRFSGFLSQNG 11.241 8.03
363 T CMGC/MAPK/ERK/Erk2 RASFPPGTPVTLPEE 20.942 4.61
14 S CK1/VRK/VRK2 PYGAPPFSNRAPDGE 11.75 4
363 T CMGC/CDK/CDK2/CDC28 RASFPPGTPVTLPEE 14.806 9.411
215 Y TK/Met/RON ADADAAAYSWAHPGY 11.25 9.3
55 T STE/STE7/MEK1/MAP2K2 YPEDEVLTEWFSDCA 14 7
575 T CMGC/MAPK/JNK/JNK2 PLVRLLHTPGHFQPL 27.235 6.118
416 S AGC/NDR/NDR/NDR1 LDSRERFSSDGLSGT 11 6
575 T AGC/GRK/BARK/BARK1 PLVRLLHTPGHFQPL 11.286 3.384
417 S CAMK/CAMKL/QIK/SIK2 DSRERFSSDGLSGTP 11.167 5.721
59 S Atypical/PDHK EVLTEWFSDCATIGG 13.286 2.003
417 S CMGC/DYRK/DYRK2 DSRERFSSDGLSGTP 11.444 7.053
421 S Atypical/PIKK/FRAP RFSSDGLSGTPASGL 12.667 8.145
36 T CMGC/MAPK/JNK/JNK3 PQGTAGGTPPLRDDP 11.375 6.781
36 T CMGC/CDK/CDK5 PQGTAGGTPPLRDDP 14.465 6.616
553 Y TK/EGFR QEEPDGTYVRYTSHP 15.422 6.45
417 S CAMK/PIM DSRERFSSDGLSGTP 11.381 4.683
363 T CMGC/CDK/CDK5/CDK5 RASFPPGTPVTLPEE 14.222 7.867
417 S CAMK/PIM/PIM1 DSRERFSSDGLSGTP 16.154 5.965
8 Y TK/Jak/JAK2 MWHNINPYGAPPFSN 14.318 9.766
14 S Other/NEK/NEK11 PYGAPPFSNRAPDGE 17.333 8.933
36 T CMGC/MAPK/JNK/JNK2 PQGTAGGTPPLRDDP 31.441 6.118
363 T CMGC/MAPK/JNK/JNK2 RASFPPGTPVTLPEE 40.706 6.118
507 S CAMK/MAPKAPK/MK5/MAPKAPK5 RRVREALSAQGVDLV 12.909 6.633
294 T CAMK/MAPKAPK/MK5 DAIDRSITLLRSFSA 13.273 6.633
423 T CMGC/MAPK/ERK/Erk1 SSDGLSGTPASGLPE 13.993 10.326
523 Y TK/Trk/TRKA ARGEIDIYGGPGSYL 12 11.95
446 S CMGC/MAPK/p38/HOG1 PDGAPFVSMRDAVPP 13.4 7.46
179 T Other/TTK/TTK DGYSVNLTTSARAYS 49.636 47.968
36 T Atypical/PIKK/FRAP PQGTAGGTPPLRDDP 16.722 8.145
294 T CAMK/MAPKAPK/MK5/MAPKAPK5 DAIDRSITLLRSFSA 13.273 6.633
553 Y TK/Src/SrcA/FGR QEEPDGTYVRYTSHP 12.2 8.74
55 T Other/TTK/TTK YPEDEVLTEWFSDCA 49.818 47.968
463 S TKL/LISK/LIMK/LIMK1 PDGVGFASGEGLSCL 14 6
463 S TKL/LISK/LIMK PDGVGFASGEGLSCL 14 6
401 S CK1/CK1/CK1-D/CSNK1D HGPADSDSVFGGLAP 15.45 8.142
423 T CMGC/MAPK/JNK/JNK2 SSDGLSGTPASGLPE 26.147 6.118

* Only the results whose Scores are more than 10 are listed here.

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Pfam Domains (Experimental/Computational Results)

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id type start end
Sorry. There is no result for this protein entry.

Mutation (Experimental Results)

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POSITION WILD-TYPE AA MUTANT DISEASE/NOTES REFERENCE
Sorry. There is no result for this protein entry.

Pathway (Experimental Results)

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Pathway Accession Number Description
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Multiple Sequence Alignments (Computational Results)

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  • Sorry. There is no multiple sequence alignment information for this entry.

Protein Alignment (Computational Results)

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  • Sorry. There is no ortholog information for this entry.
  • Sorry. There is no alignment file for this entry.