Comprehensive Information

Detailed Information (Experimental Results)

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Database ID43
UniProt ID A2S1Q1 
Name Effector protein BipC
Type Type III secretion system effector (T3SE)
Gene Name bipC
Organism Burkholderia mallei
Gene Ontology Terms GO:0005576;GO:0009405
Function -
Sequence MSIGVQSSGINISHAELSRLVDAGKSEQGDKAVRDDGRALARADAALAAVVGERVAARRDAVAGSGAQRVELARPKPDAQTRATDRRTVSGLEREHKRLAASQTPRVTGMHDALVQRHVSLDGAKAAHGEGVKRAAGDAPRAAADAPQRFAFADDKAFDAMLALGAAMQKNVQSDLAMQGKLTMLAHDAMMSAAAQDRSIGAAQMTAAIAGGALQATTSLGGAMQQMKSLSTKSMSIEKELKPQAELKQFHAEQALELRGINKPVLSNDEVSHVKIKRDTGETVRHEIDHGGERMSDEHASVLAQEAPARQHRIDMHGMRHEENLVKAGRQQMKGDLLQSGGQIGKNQIDGASAQQQGADRAEQKEDENAQQTAMAAASTRDEAAHRSREAAQKAIDAAKSQVANDNAVAAQVAGNLRT
Length 419  amino acids
Reference 24391954
IBS
There is no IBS picture for this protein entry.
Sequence Alignment:

Protein Structure (Experimental Results)

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PDB Accession Method Resolution Chain Structure Review
Sorry. There is no result for this protein entry.

Disorder Prediction (Computational Results)

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Start End Sequence
261 419 INKPVLSNDEVSHVKIKRDTGETVRHEIDHGGERMSDEHASVLAQEAPARQHRIDMHGMRHEENLVKAGRQQMKGDLLQSGGQIGKNQIDGASAQQQGADRAEQKEDENAQQTAMAAASTRDEAAHRSREAAQKAIDAAKSQVANDNAVAAQVAGNLRT
1 259 MSIGVQSSGINISHAELSRLVDAGKSEQGDKAVRDDGRALARADAALAAVVGERVAARRDAVAGSGAQRVELARPKPDAQTRATDRRTVSGLEREHKRLAASQTPRVTGMHDALVQRHVSLDGAKAAHGEGVKRAAGDAPRAAADAPQRFAFADDKAFDAMLALGAAMQKNVQSDLAMQGKLTMLAHDAMMSAAAQDRSIGAAQMTAAIAGGALQATTSLGGAMQQMKSLSTKSMSIEKELKPQAELKQFHAEQALELR

Disorder Picture (Computational Results)

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Kinase-specific Phosphorylation Sites (Computational Results)

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Position Code Kinase Peptide Score Cutoff
231 S AGC/RSK/MSK/RPS6KA5 MQQMKSLSTKSMSIE 12.222 8.69
272 S AGC/GRK VLSNDEVSHVKIKRD 12.603 6.103
120 S CAMK/MAPKAPK ALVQRHVSLDGAKAA 11.117 6.36
379 S CAMK/MAPKAPK/MNK/MNK1 QTAMAAASTRDEAAH 11.5 8.333
104 T CMGC/CDK/CDK2/CDC28 KRLAASQTPRVTGMH 11.472 9.411
231 S CAMK/MAPKAPK MQQMKSLSTKSMSIE 11.013 6.36
120 S CAMK/MAPKAPK/MK5 ALVQRHVSLDGAKAA 12.182 6.633
88 T Other/IKK/IKKb/IKBKB TRATDRRTVSGLERE 11.323 6.297
272 S AGC/PKC/PKCa/PRKCB VLSNDEVSHVKIKRD 27.328 8.434
90 S AGC/AKT/AKT2 ATDRRTVSGLEREHK 13.143 6.504
419 T AGC/GRK/BARK QVAGNLRT******* 13.302 3.806
13 S CK1/VRK/VRK2 QSSGINISHAELSRL 16 4
120 S CAMK/CAMKL/CHK1 ALVQRHVSLDGAKAA 11.69 8.03
379 S Other/PLK QTAMAAASTRDEAAH 11.448 8.093
353 S CAMK/RAD53/DUN1 KNQIDGASAQQQGAD 11 6.017
301 S CAMK/MAPKAPK/MNK/MNK1 RMSDEHASVLAQEAP 11 8.333
229 S AGC/PKC/PKCi GAMQQMKSLSTKSMS 11.333 7.442
18 S Other/PEK/PEK NISHAELSRLVDAGK 13 6.95
7 S CK1/VRK/VRK2 *MSIGVQSSGINISH 18.5 4
236 S AGC/PKC/PKCa/PRKCB SLSTKSMSIEKELKP 11.207 8.434
104 T CMGC/CDK/CDK5 KRLAASQTPRVTGMH 15.242 6.616
104 T CMGC/MAPK/p38/MAPK11 KRLAASQTPRVTGMH 11.815 5.425
236 S CAMK/MAPKAPK SLSTKSMSIEKELKP 12.623 6.36
90 S CAMK/CAMKL/CHK1 ATDRRTVSGLEREHK 11.793 8.03
183 T Other/TTK/TTK LAMQGKLTMLAHDAM 49.818 47.968
183 T CAMK/MAPKAPK/MK5/MAPKAPK5 LAMQGKLTMLAHDAM 14.455 6.633
280 T STE/STE20/MST/MST1 HVKIKRDTGETVRHE 12.548 2.612
90 S CAMK/CAMKL/QIK ATDRRTVSGLEREHK 12.235 5.111
102 S Atypical/PIKK/ATR/ATR EHKRLAASQTPRVTG 12.364 5.038
231 S CAMK/MAPKAPK/MK5/MAPKAPK5 MQQMKSLSTKSMSIE 11 6.633
219 S Other/IKK GALQATTSLGGAMQQ 13.038 4.573
90 S CAMK/MAPKAPK/MK5 ATDRRTVSGLEREHK 11.727 6.633
104 T CMGC/CDK/CDK5/PHO85 KRLAASQTPRVTGMH 12.389 7.061
183 T CAMK/MAPKAPK/MNK LAMQGKLTMLAHDAM 11.556 5.685
104 T CMGC/MAPK/JNK/JNK2 KRLAASQTPRVTGMH 33.971 6.118
8 S TKL/LISK/LIMK MSIGVQSSGINISHA 11 6
2 S CAMK/CAMKL/QIK/SIK1 ******MSIGVQSSG 12 2.597
104 T CMGC/MAPK/ERK/Erk4 KRLAASQTPRVTGMH 13.333 5.7
219 S CAMK/CAMKL GALQATTSLGGAMQQ 13.032 6.355
90 S CAMK/MAPKAPK ATDRRTVSGLEREHK 11.468 6.36
231 S CAMK/MAPKAPK/MK5 MQQMKSLSTKSMSIE 11 6.633
8 S CK1/VRK/VRK2 MSIGVQSSGINISHA 17 4
18 S Other/PEK/PEK/EIF2AK3 NISHAELSRLVDAGK 13 6.95
2 S Other/PLK ******MSIGVQSSG 16.208 8.093
84 T CAMK/DAPK/DAPK/DAPK2 PDAQTRATDRRTVSG 11 1.286
353 S Other/CDC7/CDC7 KNQIDGASAQQQGAD 15.333 9.583
104 T CMGC/MAPK/ERK/Erk2 KRLAASQTPRVTGMH 12.084 4.61
2 S CK1/VRK/VRK2 ******MSIGVQSSG 21.25 4
419 T AGC/GRK QVAGNLRT******* 15.888 6.103
419 T AGC/PKC/PKCa/PRKCA QVAGNLRT******* 23.056 5.842
120 S AGC/PKC/PKCi ALVQRHVSLDGAKAA 13.521 7.442
283 T Other/TTK/TTK IKRDTGETVRHEIDH 57.182 47.968
183 T CAMK/MAPKAPK/MK5 LAMQGKLTMLAHDAM 14.455 6.633
104 T CMGC/CDK/CDK2/CDK2 KRLAASQTPRVTGMH 14.933 6.826
104 T CMGC/MAPK/ERK/Erk1 KRLAASQTPRVTGMH 20.035 10.326
301 S Atypical/Alpha/ChaK/TRPM7 RMSDEHASVLAQEAP 12.857 4.914
13 S Other/PLK QSSGINISHAELSRL 13.474 8.093
280 T STE/STE20/PAKA HVKIKRDTGETVRHE 21.907 6.397
102 S Other/CDC7 EHKRLAASQTPRVTG 12.667 9.583
90 S CAMK/MAPKAPK/MK5/MAPKAPK5 ATDRRTVSGLEREHK 11.727 6.633
102 S Other/CDC7/CDC7 EHKRLAASQTPRVTG 12.667 9.583
419 T AGC/GRK/BARK/BARK1 QVAGNLRT******* 22.786 3.384
120 S CAMK/MAPKAPK/MK5/MAPKAPK5 ALVQRHVSLDGAKAA 12.182 6.633
419 T Other/PEK QVAGNLRT******* 17.227 2.678
8 S TKL/LISK MSIGVQSSGINISHA 12 3.062
353 S Other/CDC7 KNQIDGASAQQQGAD 15.333 9.583
8 S TKL/LISK/LIMK/LIMK1 MSIGVQSSGINISHA 11 6

* Only the results whose Scores are more than 10 are listed here.

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Pfam Domains (Experimental/Computational Results)

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id type start end
IpaC_SipC Pfam 34 407

Mutation (Experimental Results)

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POSITION WILD-TYPE AA MUTANT DISEASE/NOTES REFERENCE
Sorry. There is no result for this protein entry.

Pathway (Experimental Results)

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Pathway Accession Number Description
Sorry. There is no result for this protein entry.

Multiple Sequence Alignments (Computational Results)

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Protein Alignment (Computational Results)

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