Comprehensive Information
Detailed Information (Experimental Results)
| Database ID | 44 |
| UniProt ID |
A2S1Q3
|
| Name |
Translocator protein BipD
|
| Type |
Type III secretion system effector (T3SE)
|
| Gene Name |
bipD
|
| Organism |
Burkholderia mallei
|
| Gene Ontology Terms |
GO:0005576;GO:0009405
|
| Function |
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane (By similarity).
|
| Sequence |
MNMHVDMGRALTVRDWPALEALAKTMPADAGARAMTDDDLRAAGVDRRVPEQKLGAAIDEFASLRLPDRIDGRFVDGRRANLTVFDDARVAVRGHARAQRNLLERLETELLGGTLDTAGDEGGIQPDPILQGLVDVIGQGKSDIDAYATIVEGLTKYFQSVADVMSKLQDYISAKDDKNMKIDGGKIKALIQQVIDHLPTMQLPKGADIARWRKELGDAVSISDSGVVTINPDKLIKMRDSLPPDGTVWDTARYQAWNTAFSGQKDNIQNDVQTLVEKYSHQNSNFDNLVKVLSGAISTLTDTAKSYLQI
|
| Length |
310 amino acids
|
| Reference |
24391954
|
| IBS |
|
Protein Structure (Experimental Results)
| PDB Accession |
Method |
Resolution |
Chain |
Structure Review |
| Sorry. There is no result for this protein entry. |
Disorder Prediction (Computational Results)
| Start |
End |
Sequence |
| 105 |
109 |
RLETE |
| 95 |
103 |
HARAQRNLL |
| 113 |
125 |
GTLDTAGDEGGIQ |
| 278 |
279 |
KY |
| 173 |
183 |
SAKDDKNMKID |
| 282 |
283 |
QN |
| 304 |
310 |
AKSYLQI |
| 1 |
6 |
MNMHVD |
| 265 |
267 |
KDN |
| 17 |
59 |
PALEALAKTMPADAGARAMTDDDLRAAGVDRRVPEQKLGAAID |
Disorder Picture (Computational Results)
Kinase-specific Phosphorylation Sites (Computational Results)
| Position |
Code |
Kinase |
Peptide |
Score |
Cutoff |
| 299 |
T |
AGC/GRK/BARK |
VLSGAISTLTDTAKS |
14.349 |
3.806 |
| 306 |
S |
AGC/GRK/BARK |
TLTDTAKSYLQI*** |
16.86 |
3.806 |
| 155 |
T |
STE/STE20/MST/MST1 |
ATIVEGLTKYFQSVA |
21.387 |
2.612 |
| 229 |
T |
Other/TTK/TTK |
ISDSGVVTINPDKLI |
49.091 |
47.968 |
| 36 |
T |
CMGC/CK2 |
DAGARAMTDDDLRAA |
11.233 |
7.389 |
| 254 |
Y |
TK/Csk/CTK |
TVWDTARYQAWNTAF |
13 |
10 |
| 108 |
T |
CMGC/DYRK/DYRK2 |
NLLERLETELLGGTL |
12.111 |
7.053 |
| 306 |
S |
AGC/GRK/BARK/BARK1 |
TLTDTAKSYLQI*** |
30.214 |
3.384 |
| 306 |
S |
Atypical/PDHK/PDHK |
TLTDTAKSYLQI*** |
24.925 |
2.805 |
| 307 |
Y |
TK/Met/RON |
LTDTAKSYLQI**** |
11.5 |
9.3 |
| 307 |
Y |
TK/Csk/CSK |
LTDTAKSYLQI**** |
18 |
9.741 |
| 259 |
T |
Other/TTK/TTK |
ARYQAWNTAFSGQKD |
56 |
47.968 |
| 274 |
T |
Other/NEK/NEK9/NEK9 |
NIQNDVQTLVEKYSH |
11 |
5.767 |
| 301 |
T |
STE/STE7/MEK1/MAP2K2 |
SGAISTLTDTAKSYL |
11 |
7 |
| 301 |
T |
CK1/TTBK/TTBK1 |
SGAISTLTDTAKSYL |
11.5 |
5.133 |
| 108 |
T |
Other/TTK/TTK |
NLLERLETELLGGTL |
57.636 |
47.968 |
| 306 |
S |
AGC/PKC/PKCa/PRKCA |
TLTDTAKSYLQI*** |
16.535 |
5.842 |
| 299 |
T |
STE/STE20/MSN/MINK1 |
VLSGAISTLTDTAKS |
11 |
7 |
| 36 |
T |
CAMK/MAPKAPK/MK5/MAPKAPK5 |
DAGARAMTDDDLRAA |
14.636 |
6.633 |
| 303 |
T |
AGC/GRK/BARK |
AISTLTDTAKSYLQI |
12.326 |
3.806 |
| 299 |
T |
STE/STE20/MSN/TNIK |
VLSGAISTLTDTAKS |
11 |
7 |
| 299 |
T |
AGC/GRK/GRK/GRK |
VLSGAISTLTDTAKS |
14.389 |
6.878 |
| 149 |
T |
Other/TTK/TTK |
SDIDAYATIVEGLTK |
54 |
47.968 |
| 294 |
S |
AGC/GRK |
DNLVKVLSGAISTLT |
11.948 |
6.103 |
| 299 |
T |
STE/STE20/MSN/MAP4K4 |
VLSGAISTLTDTAKS |
11 |
7 |
| 147 |
Y |
TK/Eph |
GKSDIDAYATIVEGL |
16.268 |
7.03 |
| 63 |
S |
AGC/GRK |
AAIDEFASLRLPDRI |
11.819 |
6.103 |
| 12 |
T |
AGC/PKC/PKCh |
VDMGRALTVRDWPAL |
12.769 |
4.771 |
| 36 |
T |
CMGC/DYRK/DYRK2 |
DAGARAMTDDDLRAA |
11.167 |
7.053 |
| 298 |
S |
TKL/STKR/STKR1 |
KVLSGAISTLTDTAK |
13.375 |
6.85 |
| 284 |
S |
CAMK/MAPKAPK/MNK/MNK2 |
EKYSHQNSNFDNLVK |
11.857 |
6.869 |
| 36 |
T |
CAMK/MAPKAPK |
DAGARAMTDDDLRAA |
11.857 |
6.36 |
| 36 |
T |
CK1/CK1/CK1-D/CK1e |
DAGARAMTDDDLRAA |
11.941 |
4.55 |
| 307 |
Y |
TK/Csk |
LTDTAKSYLQI**** |
14.185 |
4.128 |
| 36 |
T |
CAMK/MAPKAPK/MK5 |
DAGARAMTDDDLRAA |
14.636 |
6.633 |
| 306 |
S |
AGC/PKC/PKCa/PRKCB |
TLTDTAKSYLQI*** |
14.655 |
8.434 |
| 299 |
T |
Atypical/PDHK/PDHK/PDK1 |
VLSGAISTLTDTAKS |
17.703 |
2.714 |
| 274 |
T |
Other/NEK/NEK9 |
NIQNDVQTLVEKYSH |
11 |
5.767 |
| 303 |
T |
AGC/PKC/PKCa/PRKCA |
AISTLTDTAKSYLQI |
17.01 |
5.842 |
| 299 |
T |
AGC/GRK/BARK/BARK1 |
VLSGAISTLTDTAKS |
13.286 |
3.384 |
| 306 |
S |
Other/PEK |
TLTDTAKSYLQI*** |
15.045 |
2.678 |
| 25 |
T |
Atypical/PIKK/FRAP |
ALEALAKTMPADAGA |
11.278 |
8.145 |
| 254 |
Y |
TK/Met/RON |
TVWDTARYQAWNTAF |
11.5 |
9.3 |
| 12 |
T |
CK1/VRK/VRK2 |
VDMGRALTVRDWPAL |
15.5 |
4 |
| 303 |
T |
STE/STE20/MST/MST1 |
AISTLTDTAKSYLQI |
15.129 |
2.612 |
* Only the results whose Scores are more than 10 are listed here.
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Pfam Domains (Experimental/Computational Results)
| id |
type |
start |
end |
| IpaD |
Pfam |
127 |
308 |
Mutation (Experimental Results)
| POSITION |
WILD-TYPE AA |
MUTANT |
DISEASE/NOTES |
REFERENCE |
| Sorry. There is no result for this protein entry. |
Pathway (Experimental Results)
| Pathway Accession Number |
Description |
| Sorry. There is no result for this protein entry. |
Multiple Sequence Alignments (Computational Results)
Protein Alignment (Computational Results)
