Comprehensive Information
Detailed Information (Experimental Results)
| Database ID | 46 |
| UniProt ID |
A2S1Q9
|
| Name |
Effector protein BopA
|
| Type |
Type III secretion system effector (T3SE)
|
| Gene Name |
bopA
|
| Organism |
Burkholderia mallei
|
| Gene Ontology Terms |
GO:0005615;GO:0009405
|
| Function |
Plays a role in mediating bacterial evasion from the host autophagic pathway.
|
| Sequence |
MINVGAFVASARSGARVVVGGDARGPVVSAARLGMKERLFAFLAHVPLLKHCDAVRRYAEQVRMENRRSLEVFVLALSKRYGPEGAKAAFDYGARRDGAPLDQRRVRNMVSIAEHFHGTGDAKPLARQMVFRSWECRGLDHPGHASLTIKNQADADAGRHVYEHVSWWPNQRLGSKEHFDRIEPKTLDGYRIDKRSEISSATEQRLREGDAARRKILADGFKYANQDERHDALFFPRAGQKLDKDAEWGLSARKVYFPAIGFNHDRRDTDRPRAFVLFGLNEAAMLRDARTVKEGAKSGELKYRMISKKENCASMALRVLRAGGAEHFVPYTAAWISEDPNHAHAYALAVQARIDALNQRRADVERRCERLRDSASVRQAWRAFSEAGGASASPLAEDAGRGRASAHMRQARLDEHAREVERIGAYFAELSAGRSGKHRDRADADLADAMKRCAPSARDDVAALTRKASVLVETLGRHLDAPPPSDSSALRRLAAHAMIGRIEAFMAAAIAA
|
| Length |
512 amino acids
|
| Reference |
24391954
|
| IBS |
|
Protein Structure (Experimental Results)
| PDB Accession |
Method |
Resolution |
Chain |
Structure Review |
| Sorry. There is no result for this protein entry. |
Disorder Prediction (Computational Results)
| Start |
End |
Sequence |
| 152 |
152 |
Q |
| 360 |
493 |
RRADVERRCERLRDSASVRQAWRAFSEAGGASASPLAEDAGRGRASAHMRQARLDEHAREVERIGAYFAELSAGRSGKHRDRADADLADAMKRCAPSARDDVAALTRKASVLVETLGRHLDAPPPSDSSALRRL |
| 503 |
512 |
EAFMAAAIAA |
| 63 |
63 |
R |
| 182 |
186 |
IEPKT |
| 268 |
269 |
DT |
| 290 |
303 |
RTVKEGAKSGELKY |
| 98 |
102 |
GAPLD |
| 1 |
4 |
MINV |
| 189 |
219 |
GYRIDKRSEISSATEQRLREGDAARRKILAD |
| 221 |
227 |
FKYANQD |
| 308 |
309 |
KK |
Disorder Picture (Computational Results)
Kinase-specific Phosphorylation Sites (Computational Results)
| Position |
Code |
Kinase |
Peptide |
Score |
Cutoff |
| 393 |
S |
CMGC/CDK/CDK5/CDK5 |
EAGGASASPLAEDAG |
20.247 |
7.867 |
| 202 |
T |
CK1/CK1/CK1-D/CSNK1D |
RSEISSATEQRLREG |
12.9 |
8.142 |
| 469 |
S |
CAMK/MAPKAPK |
AALTRKASVLVETLG |
12.052 |
6.36 |
| 385 |
S |
CAMK/MAPKAPK |
RQAWRAFSEAGGASA |
17.182 |
6.36 |
| 307 |
S |
AGC/AKT/AKT2 |
ELKYRMISKKENCAS |
12 |
6.504 |
| 175 |
S |
STE/STE20/MST |
WPNQRLGSKEHFDRI |
50.658 |
3.532 |
| 69 |
S |
AGC/RSK/RSKp90/RPS6KA3 |
VRMENRRSLEVFVLA |
11.029 |
8.112 |
| 13 |
S |
AGC/PKC/PKCa/PRKCB |
AFVASARSGARVVVG |
11.931 |
8.434 |
| 376 |
S |
CAMK/MAPKAPK/MNK/MNK1 |
ERLRDSASVRQAWRA |
11 |
8.333 |
| 469 |
S |
CAMK/MAPKAPK/MNK/MNK1 |
AALTRKASVLVETLG |
11 |
8.333 |
| 393 |
S |
CMGC/MAPK |
EAGGASASPLAEDAG |
11.307 |
4.55 |
| 69 |
S |
CAMK/DAPK/DAPK |
VRMENRRSLEVFVLA |
11.341 |
3.493 |
| 405 |
S |
Other/CDC7/CDC7 |
DAGRGRASAHMRQAR |
15.333 |
9.583 |
| 391 |
S |
Other/CDC7/CDC7 |
FSEAGGASASPLAED |
15.333 |
9.583 |
| 405 |
S |
CAMK/RAD53/DUN1 |
DAGRGRASAHMRQAR |
11 |
6.017 |
| 162 |
Y |
TK/Fer/FER |
ADAGRHVYEHVSWWP |
11 |
5.02 |
| 385 |
S |
STE/STE20/MST/MST1 |
RQAWRAFSEAGGASA |
15.548 |
2.612 |
| 405 |
S |
Other/CDC7 |
DAGRGRASAHMRQAR |
15.333 |
9.583 |
| 391 |
S |
CAMK/RAD53/DUN1 |
FSEAGGASASPLAED |
11 |
6.017 |
| 58 |
Y |
TK/PDGFR |
HCDAVRRYAEQVRME |
11.722 |
5.435 |
| 69 |
S |
AGC/PKC/PKCa/PRKCB |
VRMENRRSLEVFVLA |
12.103 |
8.434 |
| 469 |
S |
AGC/RSK/RSKp90/RPS6KA3 |
AALTRKASVLVETLG |
11.353 |
8.112 |
| 10 |
S |
CK1/VRK/VRK2 |
NVGAFVASARSGARV |
18.25 |
4 |
| 307 |
S |
AGC/RSK/MSK/RPS6KA5 |
ELKYRMISKKENCAS |
13.259 |
8.69 |
| 393 |
S |
CMGC/CDK/CDK2/CDC28 |
EAGGASASPLAEDAG |
13.778 |
9.411 |
| 303 |
Y |
TK/Fer/FER |
AKSGELKYRMISKKE |
13.1 |
5.02 |
| 393 |
S |
CAMK/MAPKAPK |
EAGGASASPLAEDAG |
12.065 |
6.36 |
| 391 |
S |
Other/CDC7 |
FSEAGGASASPLAED |
15.333 |
9.583 |
| 393 |
S |
CMGC/MAPK/JNK/JNK2 |
EAGGASASPLAEDAG |
29.794 |
6.118 |
| 303 |
Y |
TK/Src/SrcB/HCK |
AKSGELKYRMISKKE |
14.967 |
6.378 |
| 10 |
S |
Other/CDC7 |
NVGAFVASARSGARV |
15.333 |
9.583 |
| 314 |
S |
STE/STE20/KHS |
SKKENCASMALRVLR |
11.75 |
6.762 |
| 385 |
S |
AGC/RSK/MSK/RPS6KA5 |
RQAWRAFSEAGGASA |
14.778 |
8.69 |
| 385 |
S |
STE/STE20/PAKA/PAK1 |
RQAWRAFSEAGGASA |
12.395 |
6.979 |
| 81 |
Y |
TK/Csk/CSK |
VLALSKRYGPEGAKA |
18.222 |
9.741 |
| 202 |
T |
CK1/CK1/CK1-D/CK1e |
RSEISSATEQRLREG |
11.529 |
4.55 |
| 13 |
S |
CK1/VRK/VRK2 |
AFVASARSGARVVVG |
13.25 |
4 |
| 469 |
S |
STE/STE20/PAKA/PAK1 |
AALTRKASVLVETLG |
12 |
6.979 |
| 376 |
S |
CK1/CK1/CK1-D/CSNK1D |
ERLRDSASVRQAWRA |
11 |
8.142 |
| 196 |
S |
CK1/CK1/CK1-D/CSNK1D |
GYRIDKRSEISSATE |
12.45 |
8.142 |
| 431 |
S |
CMGC/CDK/CDK2/CDC28 |
GAYFAELSAGRSGKH |
12.222 |
9.411 |
| 393 |
S |
CMGC/MAPK/p38 |
EAGGASASPLAEDAG |
12.067 |
4.309 |
| 10 |
S |
CAMK/RAD53/DUN1 |
NVGAFVASARSGARV |
11 |
6.017 |
| 69 |
S |
Other/AUR/AurB/AURKB |
VRMENRRSLEVFVLA |
11.173 |
7.551 |
| 393 |
S |
CMGC/CDK/CDK5/PHO85 |
EAGGASASPLAEDAG |
11.5 |
7.061 |
| 456 |
S |
CAMK/CAMKL/PASK/PASK |
AMKRCAPSARDDVAA |
11.167 |
5.4 |
| 190 |
Y |
TK/Trk/TRKA |
EPKTLDGYRIDKRSE |
13.4 |
11.95 |
| 10 |
S |
Other/CDC7/CDC7 |
NVGAFVASARSGARV |
15.333 |
9.583 |
| 393 |
S |
CMGC/CDK/CDK5 |
EAGGASASPLAEDAG |
14.828 |
6.616 |
| 385 |
S |
AGC/RSK/RSKp90/RPS6KA3 |
RQAWRAFSEAGGASA |
11.088 |
8.112 |
| 393 |
S |
CMGC/MAPK/ERK/Erk1 |
EAGGASASPLAEDAG |
24.639 |
10.326 |
| 469 |
S |
CMGC/DYRK/DYRK2 |
AALTRKASVLVETLG |
13.056 |
7.053 |
| 469 |
S |
CAMK/CAMKL/AMPK/AMPKA1 |
AALTRKASVLVETLG |
15.25 |
5.312 |
* Only the results whose Scores are more than 10 are listed here.
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Pfam Domains (Experimental/Computational Results)
| id |
type |
start |
end |
| SicP- |
Pfam |
31 |
114 |
Mutation (Experimental Results)
| POSITION |
WILD-TYPE AA |
MUTANT |
DISEASE/NOTES |
REFERENCE |
| Sorry. There is no result for this protein entry. |
Pathway (Experimental Results)
| Pathway Accession Number |
Description |
| Sorry. There is no result for this protein entry. |
Multiple Sequence Alignments (Computational Results)
Protein Alignment (Computational Results)
