Comprehensive Information
Detailed Information (Experimental Results)
| Database ID | 6 |
| UniProt ID |
A0FKE4
|
| Name |
AexT
|
| Type |
Type III secretion system effector (T3SE)
|
| Gene Name |
aexT
|
| Organism |
Aeromonas veronii
|
| Gene Ontology Terms |
GO:0005576;GO:0005096;GO:0009405
|
| Function |
-
|
| Sequence |
MQIQANTVGTQAVAHHSDAPTGVGRMGQLEARQVATGQDAILLGNRSEPQKGQGLLSRLGAQLARPFVAIKEWIGNLLGSGKSAAAPKTQVAENLSMADQKRLFLQKALPYTLSALDKTSELKSINAEQLRKDHTTLATGNGALRSLVTALSGIRDGSKIEATTHQAARLLELNLGGIALQQWGTTGRQASEWVSSATQEQLGEVAAGLNDLMHEVAQLRYAVESEVKGEPADKVLAEGLQNQFGLEAEQYLGEQPHGLYSDAEVMALGLYTNGEYQHLNRSLRQEKQLDAGQALIDQGMSAAFEKSTPAEQLVKTFRGTHGGDAFSGVTEGQVGHDTAYFSTSRDPKVATSFGGSGTISTVFGRSGIDVSDISVEGDEQEILYNKATDMRVLLSAKDERGVTRRVLEEAKLGEQSGHSKGLLDALDLARGSGSADKPQEVDIRLKMRGLDLA
|
| Length |
453 amino acids
|
| Reference |
24391954
|
| IBS |
|
Protein Structure (Experimental Results)
| PDB Accession |
Method |
Resolution |
Chain |
Structure Review |
| Sorry. There is no result for this protein entry. |
Disorder Prediction (Computational Results)
| Start |
End |
Sequence |
| 190 |
202 |
ASEWVSSATQEQL |
| 281 |
290 |
RSLRQEKQLD |
| 253 |
253 |
G |
| 226 |
234 |
EVKGEPADK |
| 82 |
92 |
KSAAAPKTQVA |
| 112 |
141 |
TLSALDKTSELKSINAEQLRKDHTTLATGN |
| 396 |
453 |
AKDERGVTRRVLEEAKLGEQSGHSKGLLDALDLARGSGSADKPQEVDIRLKMRGLDLA |
| 157 |
160 |
GSKI |
| 321 |
360 |
HGGDAFSGVTEGQVGHDTAYFSTSRDPKVATSFGGSGTIS |
| 302 |
314 |
AAFEKSTPAEQLV |
| 1 |
37 |
MQIQANTVGTQAVAHHSDAPTGVGRMGQLEARQVATG |
| 45 |
55 |
NRSEPQKGQGL |
Disorder Picture (Computational Results)
Kinase-specific Phosphorylation Sites (Computational Results)
| Position |
Code |
Kinase |
Peptide |
Score |
Cutoff |
| 135 |
T |
TKL/MLK/MLK/ZAK |
EQLRKDHTTLATGNG |
11 |
7.138 |
| 316 |
T |
AGC/PDK1/PKH1 |
PAEQLVKTFRGTHGG |
11.667 |
4.167 |
| 124 |
S |
AGC/PKC/PKCi |
DKTSELKSINAEQLR |
11.208 |
7.442 |
| 432 |
S |
AGC/DMPK/ROCK |
ALDLARGSGSADKPQ |
11.532 |
6.326 |
| 260 |
Y |
TK/Fer |
GEQPHGLYSDAEVMA |
12.211 |
6.525 |
| 36 |
T |
TKL/LISK/LIMK |
LEARQVATGQDAILL |
11 |
6 |
| 361 |
T |
STE/STE20/MSN/MAP4K4 |
GGSGTISTVFGRSGI |
12 |
7 |
| 276 |
Y |
TK/Csk/CTK |
GLYTNGEYQHLNRSL |
14 |
10 |
| 342 |
S |
AGC/NDR/NDR/NDR1 |
GHDTAYFSTSRDPKV |
15 |
6 |
| 308 |
T |
CMGC/MAPK/ERK/Erk1 |
SAAFEKSTPAEQLVK |
17.944 |
10.326 |
| 191 |
S |
CMGC/DYRK/DYRK2 |
GTTGRQASEWVSSAT |
11 |
7.053 |
| 271 |
Y |
TK/Trk/TRKA |
EVMALGLYTNGEYQH |
12 |
11.95 |
| 96 |
S |
CMGC/MAPK/p38/HOG1 |
TQVAENLSMADQKRL |
13 |
7.46 |
| 57 |
S |
Other/PEK/PEK |
QKGQGLLSRLGAQLA |
13 |
6.95 |
| 149 |
T |
Other/PLK/PLK2 |
GALRSLVTALSGIRD |
13.186 |
5.114 |
| 308 |
T |
CMGC/CDK/CDK2/CDC28 |
SAAFEKSTPAEQLVK |
12.556 |
9.411 |
| 221 |
Y |
TK/PDGFR/PDGFRA |
HEVAQLRYAVESEVK |
11.5 |
8.814 |
| 361 |
T |
STE/STE20/MSN/MINK1 |
GGSGTISTVFGRSGI |
12 |
7 |
| 384 |
Y |
TK/Fak/FAK |
GDEQEILYNKATDMR |
14.625 |
4.398 |
| 419 |
S |
Other/NEK/NEK11 |
LGEQSGHSKGLLDAL |
11.333 |
8.933 |
| 198 |
T |
CK1/CK1/CK1-D/CSNK1D |
SEWVSSATQEQLGEV |
11.3 |
8.142 |
| 139 |
T |
TKL/LISK/LIMK/LIMK1 |
KDHTTLATGNGALRS |
11 |
6 |
| 225 |
S |
Other/CDC7/CDC7 |
QLRYAVESEVKGEPA |
12.667 |
9.583 |
| 308 |
T |
CMGC/CDK/CDK5/CDK5 |
SAAFEKSTPAEQLVK |
27.864 |
7.867 |
| 89 |
T |
Atypical/PIKK/FRAP |
KSAAAPKTQVAENLS |
11.75 |
8.145 |
| 403 |
T |
STE/STE20/MST/MST1 |
AKDERGVTRRVLEEA |
30.774 |
2.612 |
| 342 |
S |
AGC/NDR/NDR |
GHDTAYFSTSRDPKV |
13.5 |
6.388 |
| 191 |
S |
Other/CDC7 |
GTTGRQASEWVSSAT |
12.667 |
9.583 |
| 146 |
S |
Other/NEK/NEK9 |
TGNGALRSLVTALSG |
11 |
5.767 |
| 158 |
S |
AGC/RSK/RSKp90/RPS6KA3 |
LSGIRDGSKIEATTH |
11.706 |
8.112 |
| 308 |
T |
CMGC/CDK/CDK5 |
SAAFEKSTPAEQLVK |
12.394 |
6.616 |
| 57 |
S |
Other/PEK/PEK/EIF2AK3 |
QKGQGLLSRLGAQLA |
13 |
6.95 |
| 366 |
S |
TKL/LISK |
ISTVFGRSGIDVSDI |
16.5 |
3.062 |
| 308 |
T |
CMGC/MAPK/ERK/Erk2 |
SAAFEKSTPAEQLVK |
11.181 |
4.61 |
| 434 |
S |
CAMK/CAMKL/MARK/MARK1 |
DLARGSGSADKPQEV |
11.444 |
5.122 |
| 276 |
Y |
TK/Src/SrcA/FGR |
GLYTNGEYQHLNRSL |
11.6 |
8.74 |
| 308 |
T |
CMGC/MAPK/JNK/JNK2 |
SAAFEKSTPAEQLVK |
27.824 |
6.118 |
| 282 |
S |
AGC/PKC/PKCi |
EYQHLNRSLRQEKQL |
13.417 |
7.442 |
| 225 |
S |
Other/CDC7 |
QLRYAVESEVKGEPA |
12.667 |
9.583 |
| 308 |
T |
CMGC/CDK/CDK5/PHO85 |
SAAFEKSTPAEQLVK |
11.444 |
7.061 |
| 10 |
T |
CK1/VRK/VRK2 |
IQANTVGTQAVAHHS |
15.75 |
4 |
| 139 |
T |
TKL/LISK/LIMK |
KDHTTLATGNGALRS |
11 |
6 |
| 403 |
T |
Other/TTK/TTK |
AKDERGVTRRVLEEA |
53.273 |
47.968 |
| 186 |
T |
STE/STE7/MEK3/MAP2K3 |
ALQQWGTTGRQASEW |
12.444 |
1.477 |
| 36 |
T |
TKL/LISK/LIMK/LIMK1 |
LEARQVATGQDAILL |
11 |
6 |
| 136 |
T |
CAMK/PIM/PIM1 |
QLRKDHTTLATGNGA |
11.692 |
5.965 |
| 164 |
T |
STE/STE20/MST |
GSKIEATTHQAARLL |
11.184 |
3.532 |
| 191 |
S |
Other/CDC7/CDC7 |
GTTGRQASEWVSSAT |
12.667 |
9.583 |
| 308 |
T |
CMGC/CDK/CCRK/CDK20 |
SAAFEKSTPAEQLVK |
13.375 |
5.888 |
| 434 |
S |
CMGC/CDK/CDK2/CDC28 |
DLARGSGSADKPQEV |
12.194 |
9.411 |
| 330 |
T |
STE/STE7/MEK1/MAP2K2 |
GDAFSGVTEGQVGHD |
11 |
7 |
| 361 |
T |
STE/STE20/MSN/TNIK |
GGSGTISTVFGRSGI |
12 |
7 |
| 146 |
S |
Other/NEK/NEK9/NEK9 |
TGNGALRSLVTALSG |
11 |
5.767 |
| 185 |
T |
Other/TTK/TTK |
IALQQWGTTGRQASE |
58.909 |
47.968 |
| 7 |
T |
CK1/VRK/VRK2 |
*MQIQANTVGTQAVA |
20.5 |
4 |
| 316 |
T |
STE/STE20/YSK |
PAEQLVKTFRGTHGG |
11 |
6.05 |
* Only the results whose Scores are more than 10 are listed here.
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Pfam Domains (Experimental/Computational Results)
| id |
type |
start |
end |
| ADPrib_exo_Tox |
Pfam |
241 |
430 |
| YopE |
Pfam |
128 |
197 |
Mutation (Experimental Results)
| POSITION |
WILD-TYPE AA |
MUTANT |
DISEASE/NOTES |
REFERENCE |
| Sorry. There is no result for this protein entry. |
Pathway (Experimental Results)
| Pathway Accession Number |
Description |
| Sorry. There is no result for this protein entry. |
Multiple Sequence Alignments (Computational Results)
Protein Alignment (Computational Results)
